Clinical Investigation of the Protective Effects of Palm Vitamin E Tocotrienols on Brain White Matter

BACKGROUND AND PURPOSE—Previous cell-based and animal studies showed mixed tocotrienols are neuroprotective, but the effect is yet to be proven in humans. Thus, the present study aimed to evaluate the protective activity of mixed tocotrienols in humans with white matter lesions (WMLs). WMLs are rega...

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Veröffentlicht in:	Stroke (1970) 2014-05, Vol.45 (5), p.1422-1428
Hauptverfasser:	Gopalan, Yogheswaran, Shuaib, Ibrahim Lutfi, Magosso, Enrico, Ansari, Mukhtar Alam, Abu Bakar, Mohd Rizal, Wong, Jia Woei, Khan, Nurzalina Abdul Karim, Liong, Wei Chuen, Sundram, Kalyana, Ng, Bee Hong, Karuthan, Chinna, Yuen, Kah Hay
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Female Humans Leukoencephalopathies - blood Leukoencephalopathies - drug therapy Leukoencephalopathies - pathology Magnetic Resonance Imaging Malaysia Male Medical sciences Middle Aged Neurology Neuropharmacology Neuroprotective agent Palm Oil Pharmacology. Drug treatments Plant Oils - administration & dosage Plant Oils - adverse effects Plant Oils - pharmacology Tocotrienols - administration & dosage Tocotrienols - adverse effects Tocotrienols - pharmacology Treatment Outcome Vascular diseases and vascular malformations of the nervous system Vitamins - administration & dosage Vitamins - adverse effects Vitamins - pharmacology
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