High-level and novel mechanisms of carbapenem resistance in Gram-negative bacteria from tertiary hospitals in Nigeria

Abstract To determine the occurrence and molecular basis of carbapenem resistance in Gram-negative bacteria from tertiary hospitals in Nigeria, 182 non-duplicate Gram-negative bacterial isolates were investigated for antimicrobial susceptibility, presence of carbapenemases (tested phenotypically and...

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Veröffentlicht in:	International journal of antimicrobial agents 2014-05, Vol.43 (5), p.412-417
Hauptverfasser:	Ogbolu, D.O, Webber, M.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - analysis Bacterial Proteins - genetics beta-Lactam Resistance beta-Lactamases - analysis beta-Lactamases - genetics Carbapenem Carbapenems - pharmacology Cluster Analysis Conjugation, Genetic Genotype Gram-negative bacteria Gram-Negative Bacteria - classification Gram-Negative Bacteria - drug effects Gram-Negative Bacteria - genetics Gram-Negative Bacteria - isolation & purification Gram-Negative Bacterial Infections - microbiology Humans Hydrolysis Imipenem - metabolism Infectious Disease Microbial Sensitivity Tests Molecular Typing Nigeria Plasmids - analysis Plasmids - classification Random Amplified Polymorphic DNA Technique Resistance Sequence Analysis, DNA Tertiary Care Centers Transformation, Bacterial
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