Brain–heart crosstalk: the many faces of stress-related cardiomyopathy syndromes in anaesthesia and intensive care

Neurogenic stress cardiomyopathy (NSC) is a well-known syndrome complicating the early phase after an acute brain injury, potentially affecting outcomes. This article is a review of recent data on the putative role of localization and lateralization of brain lesions in NSC, cardiac innervation abnor...

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Veröffentlicht in:British journal of anaesthesia : BJA 2014-05, Vol.112 (5), p.803-815
Hauptverfasser: Mazzeo, A.T., Micalizzi, A., Mascia, L., Scicolone, A., Siracusano, L.
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container_title British journal of anaesthesia : BJA
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creator Mazzeo, A.T.
Micalizzi, A.
Mascia, L.
Scicolone, A.
Siracusano, L.
description Neurogenic stress cardiomyopathy (NSC) is a well-known syndrome complicating the early phase after an acute brain injury, potentially affecting outcomes. This article is a review of recent data on the putative role of localization and lateralization of brain lesions in NSC, cardiac innervation abnormalities, and new polymorphisms and other genetic causes of the sympathetic nervous system over-activity. Concerns regarding the management of stress-related cardiomyopathy syndromes during the perioperative period are also discussed. Future clinical research should explore whether specific factors explain different patient susceptibilities to the disease and should be directed towards early identification and stratification of patients at risk, so that such patients can be more carefully monitored and appropriately managed in critical care and during the perioperative period.
doi_str_mv 10.1093/bja/aeu046
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subjects Anesthesiology - methods
Brain - physiopathology
brain injuries
Brain Injuries - complications
Brain Injuries - physiopathology
Critical Care - methods
Heart - physiopathology
Humans
Monitoring, Physiologic - methods
Perioperative Care - methods
receptor cross-talk
stress cardiomyopathy
subarachnoid haemorrhage
sympathetic nervous system
Syndrome
Takotsubo Cardiomyopathy - complications
Takotsubo Cardiomyopathy - physiopathology
title Brain–heart crosstalk: the many faces of stress-related cardiomyopathy syndromes in anaesthesia and intensive care
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