Endovascular Treatment for Nontraumatic Rupture of the Descending Thoracic Aorta: Long-Term Results
Background This study evaluated the long‐term results of thoracic endovascular aortic repair (TEVAR) of nontraumatic rupture of the descending thoracic aorta. Methods This was a retrospective and observational single‐center study. During the 10‐year study period, 21 patients (6 males) with an averag...
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Veröffentlicht in: | Journal of cardiac surgery 2014-05, Vol.29 (3), p.353-358 |
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description | Background
This study evaluated the long‐term results of thoracic endovascular aortic repair (TEVAR) of nontraumatic rupture of the descending thoracic aorta.
Methods
This was a retrospective and observational single‐center study. During the 10‐year study period, 21 patients (6 males) with an average age of 66.1 ± 12.4 (range 31–81) years underwent emergency TEVAR for nontraumatic rupture of the descending thoracic aorta. The underlying aortic pathologies causing the rupture were degenerative aneurysms in 11 patients, complicated type B dissection in nine, and erosion hemorrhage due to neoplasia in one patient.
Results
The 30‐day mortality rate was 9.5% (2/21). Two patients died postoperatively: one from a repeat aortic rupture and the other from pneumonia. Two patients underwent early endovascular reintervention. After a median follow‐up of 65.6 ± 50.4 (range 1.5–44) months, 10 patients died, resulting in a late mortality of 52.6% (10/19). Six patients (31.5%) developed major complications requiring late reintervention. There was no mortality with reintervention.
Conclusions
Endovascular treatment of the descending thoracic aorta in patients with nontraumatic rupture is a promising treatment option in an emergency setting with a relatively low mortality rate. Despite encouraging early results, TEVAR is associated with a high reintervention rate and poor survival due to nonaortic or procedure‐related mortality in the long term. doi: 10.1111/jocs.12329 (J Card Surg 2014;29:353–358) |
doi_str_mv | 10.1111/jocs.12329 |
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This study evaluated the long‐term results of thoracic endovascular aortic repair (TEVAR) of nontraumatic rupture of the descending thoracic aorta.
Methods
This was a retrospective and observational single‐center study. During the 10‐year study period, 21 patients (6 males) with an average age of 66.1 ± 12.4 (range 31–81) years underwent emergency TEVAR for nontraumatic rupture of the descending thoracic aorta. The underlying aortic pathologies causing the rupture were degenerative aneurysms in 11 patients, complicated type B dissection in nine, and erosion hemorrhage due to neoplasia in one patient.
Results
The 30‐day mortality rate was 9.5% (2/21). Two patients died postoperatively: one from a repeat aortic rupture and the other from pneumonia. Two patients underwent early endovascular reintervention. After a median follow‐up of 65.6 ± 50.4 (range 1.5–44) months, 10 patients died, resulting in a late mortality of 52.6% (10/19). Six patients (31.5%) developed major complications requiring late reintervention. There was no mortality with reintervention.
Conclusions
Endovascular treatment of the descending thoracic aorta in patients with nontraumatic rupture is a promising treatment option in an emergency setting with a relatively low mortality rate. Despite encouraging early results, TEVAR is associated with a high reintervention rate and poor survival due to nonaortic or procedure‐related mortality in the long term. doi: 10.1111/jocs.12329 (J Card Surg 2014;29:353–358)</description><identifier>ISSN: 0886-0440</identifier><identifier>EISSN: 1540-8191</identifier><identifier>DOI: 10.1111/jocs.12329</identifier><identifier>PMID: 24762036</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Aorta, Thoracic - surgery ; Aortic Rupture - etiology ; Aortic Rupture - surgery ; Emergencies ; Endovascular Procedures - methods ; Endovascular Procedures - mortality ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Rupture, Spontaneous ; Time Factors ; Treatment Outcome</subject><ispartof>Journal of cardiac surgery, 2014-05, Vol.29 (3), p.353-358</ispartof><rights>2014 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3689-728e4a607b65d842905c99222a9823a270d8006c803e13ec89f9d9da782476833</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjocs.12329$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjocs.12329$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24762036$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Botsios, Spiridon</creatorcontrib><creatorcontrib>Frömke, Johannes</creatorcontrib><creatorcontrib>Walterbusch, Gerhard</creatorcontrib><creatorcontrib>Schuermann, Karl</creatorcontrib><creatorcontrib>Reinstadler, Jan</creatorcontrib><creatorcontrib>Dohmen, Guido</creatorcontrib><title>Endovascular Treatment for Nontraumatic Rupture of the Descending Thoracic Aorta: Long-Term Results</title><title>Journal of cardiac surgery</title><addtitle>J Card Surg</addtitle><description>Background
This study evaluated the long‐term results of thoracic endovascular aortic repair (TEVAR) of nontraumatic rupture of the descending thoracic aorta.
Methods
This was a retrospective and observational single‐center study. During the 10‐year study period, 21 patients (6 males) with an average age of 66.1 ± 12.4 (range 31–81) years underwent emergency TEVAR for nontraumatic rupture of the descending thoracic aorta. The underlying aortic pathologies causing the rupture were degenerative aneurysms in 11 patients, complicated type B dissection in nine, and erosion hemorrhage due to neoplasia in one patient.
Results
The 30‐day mortality rate was 9.5% (2/21). Two patients died postoperatively: one from a repeat aortic rupture and the other from pneumonia. Two patients underwent early endovascular reintervention. After a median follow‐up of 65.6 ± 50.4 (range 1.5–44) months, 10 patients died, resulting in a late mortality of 52.6% (10/19). Six patients (31.5%) developed major complications requiring late reintervention. There was no mortality with reintervention.
Conclusions
Endovascular treatment of the descending thoracic aorta in patients with nontraumatic rupture is a promising treatment option in an emergency setting with a relatively low mortality rate. Despite encouraging early results, TEVAR is associated with a high reintervention rate and poor survival due to nonaortic or procedure‐related mortality in the long term. doi: 10.1111/jocs.12329 (J Card Surg 2014;29:353–358)</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aorta, Thoracic - surgery</subject><subject>Aortic Rupture - etiology</subject><subject>Aortic Rupture - surgery</subject><subject>Emergencies</subject><subject>Endovascular Procedures - methods</subject><subject>Endovascular Procedures - mortality</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Rupture, Spontaneous</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0886-0440</issn><issn>1540-8191</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMlOwzAQhi0EomW58ADIRy4BL4ljc0NlV1REKerRMs6UBpK42A7L25NSwJexNN8_mvkQOqDkmPbv5MXZcEwZZ2oDDWmWkkRSRTfRkEgpEpKmZIB2QnghhLGUk200YGkuGOFiiOxFW7p3E2xXG4-nHkxsoI147jweuzZ60zUmVhZPumXsPGA3x3EB-ByChbas2mc8XThvbI-cOR_NKS5c-5xMwTd4AqGrY9hDW3NTB9j_rbvo8fJiOrpOirurm9FZkVgupEpyJiE1guRPIitlyhTJrFKMMaMk44blpJSECCsJB8rBSjVXpSpNLlfnSM530dF67tK7tw5C1E3Vb1nXpgXXBU0zqpigMl2hh79o99RAqZe-aoz_0n9ieoCugY-qhq__PiV6pVyvlOsf5fr2bvTw8-szyTpThQif_xnjX7XIeZ7p2fhK8_x6dl-MuS74N78wgfw</recordid><startdate>201405</startdate><enddate>201405</enddate><creator>Botsios, Spiridon</creator><creator>Frömke, Johannes</creator><creator>Walterbusch, Gerhard</creator><creator>Schuermann, Karl</creator><creator>Reinstadler, Jan</creator><creator>Dohmen, Guido</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201405</creationdate><title>Endovascular Treatment for Nontraumatic Rupture of the Descending Thoracic Aorta: Long-Term Results</title><author>Botsios, Spiridon ; Frömke, Johannes ; Walterbusch, Gerhard ; Schuermann, Karl ; Reinstadler, Jan ; Dohmen, Guido</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3689-728e4a607b65d842905c99222a9823a270d8006c803e13ec89f9d9da782476833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aorta, Thoracic - surgery</topic><topic>Aortic Rupture - etiology</topic><topic>Aortic Rupture - surgery</topic><topic>Emergencies</topic><topic>Endovascular Procedures - methods</topic><topic>Endovascular Procedures - mortality</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Rupture, Spontaneous</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Botsios, Spiridon</creatorcontrib><creatorcontrib>Frömke, Johannes</creatorcontrib><creatorcontrib>Walterbusch, Gerhard</creatorcontrib><creatorcontrib>Schuermann, Karl</creatorcontrib><creatorcontrib>Reinstadler, Jan</creatorcontrib><creatorcontrib>Dohmen, Guido</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiac surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Botsios, Spiridon</au><au>Frömke, Johannes</au><au>Walterbusch, Gerhard</au><au>Schuermann, Karl</au><au>Reinstadler, Jan</au><au>Dohmen, Guido</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endovascular Treatment for Nontraumatic Rupture of the Descending Thoracic Aorta: Long-Term Results</atitle><jtitle>Journal of cardiac surgery</jtitle><addtitle>J Card Surg</addtitle><date>2014-05</date><risdate>2014</risdate><volume>29</volume><issue>3</issue><spage>353</spage><epage>358</epage><pages>353-358</pages><issn>0886-0440</issn><eissn>1540-8191</eissn><abstract>Background
This study evaluated the long‐term results of thoracic endovascular aortic repair (TEVAR) of nontraumatic rupture of the descending thoracic aorta.
Methods
This was a retrospective and observational single‐center study. During the 10‐year study period, 21 patients (6 males) with an average age of 66.1 ± 12.4 (range 31–81) years underwent emergency TEVAR for nontraumatic rupture of the descending thoracic aorta. The underlying aortic pathologies causing the rupture were degenerative aneurysms in 11 patients, complicated type B dissection in nine, and erosion hemorrhage due to neoplasia in one patient.
Results
The 30‐day mortality rate was 9.5% (2/21). Two patients died postoperatively: one from a repeat aortic rupture and the other from pneumonia. Two patients underwent early endovascular reintervention. After a median follow‐up of 65.6 ± 50.4 (range 1.5–44) months, 10 patients died, resulting in a late mortality of 52.6% (10/19). Six patients (31.5%) developed major complications requiring late reintervention. There was no mortality with reintervention.
Conclusions
Endovascular treatment of the descending thoracic aorta in patients with nontraumatic rupture is a promising treatment option in an emergency setting with a relatively low mortality rate. Despite encouraging early results, TEVAR is associated with a high reintervention rate and poor survival due to nonaortic or procedure‐related mortality in the long term. doi: 10.1111/jocs.12329 (J Card Surg 2014;29:353–358)</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>24762036</pmid><doi>10.1111/jocs.12329</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Aorta, Thoracic - surgery Aortic Rupture - etiology Aortic Rupture - surgery Emergencies Endovascular Procedures - methods Endovascular Procedures - mortality Female Follow-Up Studies Humans Male Middle Aged Retrospective Studies Rupture, Spontaneous Time Factors Treatment Outcome |
title | Endovascular Treatment for Nontraumatic Rupture of the Descending Thoracic Aorta: Long-Term Results |
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