Expression Analysis of Leukotriene-Inflammatory Gene Interaction Network in Patients with Coronary Artery Disease

Aim: Leukotrienes are important lipid inflammatory mediators that play a pivotal role in the pathogenesis of atherosclerosis. We aimed to construct a network of interactions between leukotrienes and inflammatory biomarkers and evaluate the expression of key members of the leukotriene pathway and leu...

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Veröffentlicht in:	Journal of Atherosclerosis and Thrombosis 2014/04/24, Vol.21(4), pp.329-345
Hauptverfasser:	Nair, Jiny, Shanker, Jayashree, Jambunathan, Srikarthika, Arvind, Prathima, Kakkar, Vijay V
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Algorithms Arachidonate 5-Lipoxygenase - metabolism Case-Control Studies Coronary artery disease Coronary Artery Disease - metabolism Enzyme-Linked Immunosorbent Assay Epoxide Hydrolases - metabolism Female Gene Expression Profiling Genotype Humans Inflammation Interleukin-8 - metabolism Leukotrienes Leukotrienes - metabolism Male Middle Aged Network Polymorphism, Single Nucleotide Risk Factors Tumor Necrosis Factor-alpha - metabolism
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