Intramedullary thoracic spinal metastasis from small-cell lung cancer
Lung cancer with intramedullary spinal cord metastasis (ISCM) is a rare event exhibiting dismal prognosis. In the present paper, we describe a 74-year-old male who developed bilateral leg weakness with associated backache and non-productive cough. Chest imaging evaluation demonstrated pronounced bil...
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| Veröffentlicht in: | Monaldi archives for chest disease 2013-09, Vol.79 (3-4), p.140-142 |
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| creator | Katsenos, S Nikolopoulou, M |
| description | Lung cancer with intramedullary spinal cord metastasis (ISCM) is a rare event exhibiting dismal prognosis. In the present paper, we describe a 74-year-old male who developed bilateral leg weakness with associated backache and non-productive cough. Chest imaging evaluation demonstrated pronounced bilateral mediastinal lymphadenopathy and a nodular opacity in the right lower lobe. The patient was diagnosed with small cell lung cancer through bronchoscopic procedures. Magnetic resonance imaging of the spinal cord with contrast-enhancement revealed an intramedullary lesion consistent with metastasis at the T5-T6 level. Despite chemotherapy and thoracic spine radiotherapy, he eventually succumbed to the disease 3 months after diagnosis. A brief overview of the current literature is also provided laying emphasis on the therapeutic strategies of this unusual extrathoracic metastatic disease. |
| doi_str_mv | 10.4081/monaldi.2013.5214 |
| format | Article |
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A brief overview of the current literature is also provided laying emphasis on the therapeutic strategies of this unusual extrathoracic metastatic disease.</description><subject>Aged</subject><subject>Bronchoscopy</subject><subject>Carcinoma, Small Cell - diagnosis</subject><subject>Carcinoma, Small Cell - secondary</subject><subject>Diagnosis, Differential</subject><subject>Fatal Outcome</subject><subject>Humans</subject><subject>Lung Neoplasms - diagnosis</subject><subject>Lung Neoplasms - pathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Spinal Cord Neoplasms - diagnosis</subject><subject>Spinal Cord Neoplasms - secondary</subject><subject>Tomography, X-Ray Computed</subject><issn>1122-0643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PwzAQhj2AaCn8ABaUkSXF589kRFUplSoxwG45_oAgOyl2MvDvSdSCdNIt7_Pq7kHoDvCa4QoeY9_pYNs1wUDXnAC7QEsAQkosGF2g65y_MKasrvgVWhAmBXDKlmi774ako7NjCDr9FMNnn7RpTZGP7VRYRDfoPE2bC5_6WOSoQyiNC6EIY_dRGN0Zl27Qpdchu9vzXqG35-375qU8vO72m6dDaQiIoaxExSSFymoqqKdECksFWIkr4amktW1MjTVrvJTc4cYzY4VmQlrgZGJW6OHUekz99-jyoGKb51N05_oxK-BQEy5oLaconKIm9Tkn59UxtXF6UAFWsy919qVmX2r2NTH35_qxmYT8E3-y6C9iJ2ow</recordid><startdate>201309</startdate><enddate>201309</enddate><creator>Katsenos, S</creator><creator>Nikolopoulou, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201309</creationdate><title>Intramedullary thoracic spinal metastasis from small-cell lung cancer</title><author>Katsenos, S ; Nikolopoulou, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c216t-86847318da363f3276d361d7086f3739dbc90a4bf775e0bf4cd6a467d152da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Bronchoscopy</topic><topic>Carcinoma, Small Cell - diagnosis</topic><topic>Carcinoma, Small Cell - secondary</topic><topic>Diagnosis, Differential</topic><topic>Fatal Outcome</topic><topic>Humans</topic><topic>Lung Neoplasms - diagnosis</topic><topic>Lung Neoplasms - pathology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Spinal Cord Neoplasms - diagnosis</topic><topic>Spinal Cord Neoplasms - secondary</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Katsenos, S</creatorcontrib><creatorcontrib>Nikolopoulou, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Monaldi archives for chest disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Katsenos, S</au><au>Nikolopoulou, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intramedullary thoracic spinal metastasis from small-cell lung cancer</atitle><jtitle>Monaldi archives for chest disease</jtitle><addtitle>Monaldi Arch Chest Dis</addtitle><date>2013-09</date><risdate>2013</risdate><volume>79</volume><issue>3-4</issue><spage>140</spage><epage>142</epage><pages>140-142</pages><issn>1122-0643</issn><abstract>Lung cancer with intramedullary spinal cord metastasis (ISCM) is a rare event exhibiting dismal prognosis. 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| language | eng |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aged Bronchoscopy Carcinoma, Small Cell - diagnosis Carcinoma, Small Cell - secondary Diagnosis, Differential Fatal Outcome Humans Lung Neoplasms - diagnosis Lung Neoplasms - pathology Magnetic Resonance Imaging Male Spinal Cord Neoplasms - diagnosis Spinal Cord Neoplasms - secondary Tomography, X-Ray Computed |
| title | Intramedullary thoracic spinal metastasis from small-cell lung cancer |
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