Effect of Tibetan medicine zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2

To study the effect of Tibetan medicine Zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2, three different doses (1.2, 3.8 and 12 mg x kg(-1)) of Zuotai were administrated orally to rats once a day or once daily for twelve days, separately. Rats were administrated orally caffein...

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Veröffentlicht in:	Yao hsüeh hsüeh pao 2014-02, Vol.49 (2), p.267-272
Hauptverfasser:	Li, Xiang-Yang, Liu, Yong-Nian, Li, Yong-Ping, Zhu, Jun-Bo, Yao, Xing-Chen, Li, Yong-Fang, Yang, Mei, Yuan, Ming, Fan, Xue-Ru, Yin, Yue-Miao
Format:	Artikel
Sprache:	chi
Schlagworte:	Administration, Oral Animals Arylamine N-Acetyltransferase - genetics Arylamine N-Acetyltransferase - metabolism Caffeine - metabolism Caffeine - urine Cytochrome P-450 CYP1A2 - genetics Cytochrome P-450 CYP1A2 - metabolism Dose-Response Relationship, Drug Drugs, Chinese Herbal - administration & dosage Drugs, Chinese Herbal - pharmacology Female Male Medicine, Tibetan Traditional Rats Rats, Sprague-Dawley RNA, Messenger - metabolism Theophylline - urine Uracil - analogs & derivatives Uracil - urine Uric Acid - analogs & derivatives Uric Acid - urine Xanthines - urine
Online-Zugang:	Volltext
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