GPC5, a tumor suppressor, is regulated by miR-620 in lung adenocarcinoma

In the current study, a proportion of lung adenocarcinoma was shown to reduce GPC5 expression in the absence of transcriptional silencing of the tumor suppressor gene, GPC5, by aberrant methylation of CpG islands. It was hypothesized that the loss of GPC5 expression is associated with upregulation o...

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Veröffentlicht in:Molecular medicine reports 2014-06, Vol.9 (6), p.2540-2546
Hauptverfasser: ZHAO, ZHENGYUAN, HAN, CHENGGUANG, LIU, JUNTAO, WANG, CHANGLEI, WANG, YI, CHENG, LIYA
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Sprache:eng
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