Unsaturated aldehydes induce CCK secretion via TRPA1 in STC‐1 cells

SCOPE: Cholecystokinin (CCK) producing cells sense luminal contents to regulate the exocrine pancreas, gastric motility, and appetite. Although long‐chain fatty acids (FAs, ≥ C12) are well known to stimulate CCK secretion, the CCK‐releasing activities of other aliphatic compounds, such as aldehydes...

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Veröffentlicht in:	Molecular nutrition & food research 2014-05, Vol.58 (5), p.1042-1051
Hauptverfasser:	Nakajima, Shingo, Hira, Tohru, Yahagi, Asuka, Nishiyama, Chigusa, Yamashita, Takatoshi, Imagi, Jun, Hara, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	alcohols Aldehyde aldehydes Aldehydes - pharmacology Animals appetite Biological and medical sciences calcium Calcium - metabolism carbon CCK Cell Line, Tumor cholecystokinin Cholecystokinin - secretion Enteroendocrine Cells - drug effects Enteroendocrine Cells - secretion enzyme-linked immunosorbent assay fatty acids Fatty Acids - pharmacology Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology gastrointestinal motility Mice secretion Transient Receptor Potential Channels - genetics Transient Receptor Potential Channels - metabolism TRPA1 TRPA1 Cation Channel Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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