High proportion of patients with end-stage heart failure regardless of aetiology demonstrates anti-cardiac antibody deposition in failing myocardium: humoral activation, a potential contributor of disease progression

Aims Various reports have raised the possibility of humoral immune responses as contributors for the progression of heart failure. Previous studies, however, have focused on the analysis of serum and documented circulating antibodies against a variety of cardiac proteins. However, there is little ev...

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Veröffentlicht in:	European heart journal 2014-04, Vol.35 (16), p.1061-1068
Hauptverfasser:	Youker, Keith A., Assad-Kottner, Christian, Cordero-Reyes, Andrea M., Trevino, Alejandro R., Flores-Arredondo, Jose H., Barrios, Roberto, Fernandez-Sada, Evaristo, Estep, Jerry D., Bhimaraj, Arvind, Torre-Amione, Guillermo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - immunology Antibodies - metabolism Antigens - metabolism Case-Control Studies Disease Progression Female Heart Failure - immunology Humans Immunity, Humoral - immunology Immunoglobulin G - metabolism Male Middle Aged Myocardium - immunology
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