Paroxysmal Nocturnal Hemoglobinuria is rare cause for thrombosis of the intra-abdominal veins in the ethnic Indian population - results from FLAER-based flowcytometry screening

Background Paroxysmal nocturnal hemoglobinuria (PNH) may present as cytopenia, hemolysis, or thrombosis at unusual sites including splanchnic vessels. Thrombosis of the portal veins and hepatic veins are associated with thrombophilic risk factors: deficiencies of protein C, protein S, and antithromb...

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Veröffentlicht in:	European journal of haematology 2014-05, Vol.92 (5), p.435-443
Hauptverfasser:	Ahluwalia, Jasmina, Naseem, Shano, Sachdeva, Man Updesh Singh, Bose, Parveen, Bose, Sunil Kumar, Kumar, Narender, Thapa, Babu Ram, Varma, Neelam, Chawla, Yogesh Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antithrombin III - metabolism Autoantibodies - blood Bacterial Toxins Budd Chiari syndrome Child Child, Preschool extra hepatic portal vein thrombosis Female Flow Cytometry Granulocytes - metabolism Granulocytes - pathology Hemoglobinuria, Paroxysmal - blood Hemoglobinuria, Paroxysmal - complications Hemoglobinuria, Paroxysmal - diagnosis Hemoglobinuria, Paroxysmal - ethnology Hepatic Veins - metabolism Hepatic Veins - physiopathology Humans India - epidemiology Infant Intra-abdominal thrombosis Lupus Coagulation Inhibitor - blood Male Mass Screening Middle Aged Monocytes - metabolism Monocytes - pathology paroxysmal nocturnal hemoglobinuria Pore Forming Cytotoxic Proteins Portal Vein - metabolism Portal Vein - physiopathology Prospective Studies Protein C - metabolism Protein S - metabolism Risk Factors thrombophilia Thrombophilia - blood Thrombophilia - diagnosis Thrombophilia - ethnology Thrombophilia - etiology Thrombosis - blood Thrombosis - diagnosis Thrombosis - ethnology Thrombosis - etiology
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