Similar neuroprotective effects of ischemic and hypoxic preconditioning on hypoxia–ischemia in the neonatal rat: A proton MRS study

•The effects of ischemic and hypoxic preconditioning on hypoxia–ischemia (HI) were compared.•Proton MRS was used to evaluate biochemical changes after HI.•Both ischemic and hypoxic preconditioning similarly attenuate brain injury after HI.•Proton MRS lipid/N-acetyl aspartate and lipid/creatine ratio...

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Veröffentlicht in:	International journal of developmental neuroscience 2013-11, Vol.31 (7), p.616-623
Hauptverfasser:	Seo, Hyungseok, Lim, Keun Ho, Choi, Jae-Hyung, Jeong, Sung-Moon
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Animals, Newborn Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Brain - metabolism Brain - pathology Creatine - metabolism Hypoxia-Ischemia, Brain - metabolism Hypoxia-Ischemia, Brain - pathology Hypoxia–ischemia Hypoxic preconditioning In Situ Nick-End Labeling Ischemic preconditioning Ischemic Preconditioning - methods Lipids - blood Magnetic Resonance Spectroscopy Proton magnetic resonance spectroscopy Protons Rats Rats, Sprague-Dawley Spectrum Analysis Time Factors
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