Identification and biological evaluation of flavonoids from the fruits of Prunus mume

This Letter describes the identification of potent antioxidant and anti-osteoporosis agents from the fruits of Prunus mume. From the methanol extract, a novel flavan dimer, characterized as 2β,3β-epoxy-5,7,4'-trihydroxyflavan-(4α→8)-epicatechin (1), was isolated along with five known flavonoids...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2014-03, Vol.24 (5), p.1397-1402
Hauptverfasser:	Yan, Xi-Tao, Li, Wei, Sun, Ya-Nan, Yang, Seo-Young, Lee, Sang-Hyun, Chen, Jian-Bo, Jang, Hae-Dong, Kim, Young-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Animals Antioxidants - chemistry Antioxidants - isolation & purification Antioxidants - pharmacology Cell Differentiation - drug effects Cell Line Collagen - biosynthesis Flavonoids - chemistry Flavonoids - isolation & purification Flavonoids - pharmacology Free Radicals - chemistry Fruit - chemistry Fruit - metabolism Isoenzymes - metabolism Magnetic Resonance Spectroscopy Mice Molecular Conformation Prunus - chemistry Prunus - metabolism Prunus mume RANK Ligand - pharmacology Tartrate-Resistant Acid Phosphatase
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