Probiotics reduce symptoms of antibiotic use in a hospital setting: A randomized dose response study

Highlights • The tested probiotics have a dose-response effect on antibiotic associated diarrhoea (AAD). • The tested probiotics reduce incidence and duration of AAD in a dose dependent manner. • The tested probiotics reduce severity of AAD related symptoms in a dose dependent manner.

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Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2014-01, Vol.32 (4), p.458-463
Hauptverfasser:	Ouwehand, Arthur C, DongLian, Cai, Weijian, Xu, Stewart, Morgan, Ni, Jiayi, Stewart, Tad, Miller, Larry E
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Adult Aged Allergy and Immunology Anti-Bacterial Agents - adverse effects Antibiotic associated diarrhea Antibiotics Antigens Applied microbiology Bacteriology Bifidobacterium lactis Biological and medical sciences Clostridium difficile Constipation Diarrhea Diarrhea - chemically induced Diarrhea - prevention & control Disease Dose response Dose-response effects Dose-Response Relationship, Drug Drug therapy Enterocolitis, Pseudomembranous - complications Female Fundamental and applied biological sciences. Psychology Hospitals Humans Infections Inflammatory bowel disease Lactobacillus acidophilus Lactobacillus paracasei Male Microbiology Middle Aged Miscellaneous Mortality Probiotics Probiotics - therapeutic use Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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Beschreibung
Zusammenfassung:	Highlights • The tested probiotics have a dose-response effect on antibiotic associated diarrhoea (AAD). • The tested probiotics reduce incidence and duration of AAD in a dose dependent manner. • The tested probiotics reduce severity of AAD related symptoms in a dose dependent manner.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2013.11.053