Cost-effectiveness of administering 13-valent pneumococcal conjugate vaccine in addition to 23-valent pneumococcal polysaccharide vaccine to adults with immunocompromising conditions
Highlights • We model the cost effectiveness of PCV for adults with immunocompromising conditions. • We find the recommendation to be cost saving on the whole. • The recommendation saves $7 million per cohort. • This savings is largely from adults with end state renal disease. • Savings are less in...
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Veröffentlicht in: | Vaccine 2013-12, Vol.31 (50), p.6011-6021 |
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creator | Cho, Bo-Hyun Stoecker, Charles Link-Gelles, Ruth Moore, Matthew R |
description | Highlights • We model the cost effectiveness of PCV for adults with immunocompromising conditions. • We find the recommendation to be cost saving on the whole. • The recommendation saves $7 million per cohort. • This savings is largely from adults with end state renal disease. • Savings are less in other populations with worse vaccine efficacy or serotype match. |
doi_str_mv | 10.1016/j.vaccine.2013.10.024 |
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Psychology ; HIV infections ; Human immunodeficiency virus ; Humans ; Immunization ; Immunocompromised adults ; Immunocompromised Host ; immunocompromised population ; Incremental cost-effectiveness ; kidney diseases ; Male ; Microbiology ; Middle Aged ; Miscellaneous ; Models, Statistical ; Observational studies ; organ transplantation ; PCV13 ; Pneumococcal Infections - economics ; Pneumococcal Infections - prevention & control ; Pneumococcal Vaccines - administration & dosage ; Pneumococcal Vaccines - economics ; Pneumonia ; probabilistic models ; Public health ; quality-adjusted life year ; randomized clinical trials ; risk ; Streptococcus pneumoniae ; Transplants & implants ; United States ; vaccination ; Vaccination - economics ; Vaccination - methods ; Vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Young Adult</subject><ispartof>Vaccine, 2013-12, Vol.31 (50), p.6011-6021</ispartof><rights>Elsevier Ltd</rights><rights>2013 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Dec 5, 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c568t-aed99198cbaca4e1f0286bd7e6df459b77d1a53c59b0c0dec569ea55ca5745cc3</citedby><cites>FETCH-LOGICAL-c568t-aed99198cbaca4e1f0286bd7e6df459b77d1a53c59b0c0dec569ea55ca5745cc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0264410X1301400X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28010781$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24148572$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cho, Bo-Hyun</creatorcontrib><creatorcontrib>Stoecker, Charles</creatorcontrib><creatorcontrib>Link-Gelles, Ruth</creatorcontrib><creatorcontrib>Moore, Matthew R</creatorcontrib><title>Cost-effectiveness of administering 13-valent pneumococcal conjugate vaccine in addition to 23-valent pneumococcal polysaccharide vaccine to adults with immunocompromising conditions</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Highlights • We model the cost effectiveness of PCV for adults with immunocompromising conditions. • We find the recommendation to be cost saving on the whole. • The recommendation saves $7 million per cohort. • This savings is largely from adults with end state renal disease. • Savings are less in other populations with worse vaccine efficacy or serotype match.</description><subject>Acquired immune deficiency syndrome</subject><subject>Adult</subject><subject>adults</subject><subject>Aged</subject><subject>AIDS</subject><subject>Allergy and Immunology</subject><subject>Applied microbiology</subject><subject>Bacteriology</subject><subject>Biological and medical sciences</subject><subject>cost effectiveness</subject><subject>Cost-Benefit Analysis</subject><subject>disease incidence</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>HIV infections</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Immunization</subject><subject>Immunocompromised adults</subject><subject>Immunocompromised Host</subject><subject>immunocompromised population</subject><subject>Incremental cost-effectiveness</subject><subject>kidney diseases</subject><subject>Male</subject><subject>Microbiology</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Models, Statistical</subject><subject>Observational studies</subject><subject>organ transplantation</subject><subject>PCV13</subject><subject>Pneumococcal Infections - economics</subject><subject>Pneumococcal Infections - prevention & control</subject><subject>Pneumococcal Vaccines - administration & dosage</subject><subject>Pneumococcal Vaccines - economics</subject><subject>Pneumonia</subject><subject>probabilistic models</subject><subject>Public health</subject><subject>quality-adjusted life year</subject><subject>randomized clinical trials</subject><subject>risk</subject><subject>Streptococcus pneumoniae</subject><subject>Transplants & implants</subject><subject>United States</subject><subject>vaccination</subject><subject>Vaccination - economics</subject><subject>Vaccination - methods</subject><subject>Vaccines</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</subject><subject>Young Adult</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkl-L1DAUxYso7rj6EdSCCL50zE2b_nlRZPAfLPiwLuxbyCS3sxnbZDZpR-aL-fm8paMDi7A-JYTfOTm5OUnyHNgSGJRvt8u90to6XHIGOZ0tGS8eJAuoqzzjAuqHyYLxssgKYNdnyZMYt4wxkUPzODnjBRS1qPgi-bXycciwbVEPdo8OY0x9myrTW2fjgMG6TQp5tlcduiHdORx7r73Wqku1d9txowZMj1FS60hp7GC9Swef8n_rdr47RFLcqGDNSUwCZcZuiOlPO9yktu9HR5J-F3xv45SDLpzN49PkUau6iM-O63ly9enj99WX7OLb56-rDxeZFmU9ZApN00BT67XSqkBoGa_LtamwNG0hmnVVGVAi17RlmhkkVYNKCK1EVQit8_PkzexLIW5HjIOkKBq7Tjn0Y5QgoKwEE2X5HyhNP2_KCu5HKVtTcSg5oa_uoFs_BkdvJkPB65pDI4gSM6WDjzFgK3fB9iocJDA51UVu5XHMcqrLdEx1Id2Lo_u47tH8Vf3pBwGvj4CK9HVtUE7beOJqBqyqpxe9nLlWeak2gZirS7pJMAZVw2Ei3s8E0nftLQYZtUWn0dhA3ZPG23vDvrvjoDsqKcX6gQeMp7nIyCWTl1P7p_JDzqBg7Dr_DUj5Aug</recordid><startdate>20131205</startdate><enddate>20131205</enddate><creator>Cho, Bo-Hyun</creator><creator>Stoecker, Charles</creator><creator>Link-Gelles, Ruth</creator><creator>Moore, Matthew R</creator><general>Elsevier Ltd</general><general>Elsevier</general><general>Elsevier Limited</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T2</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20131205</creationdate><title>Cost-effectiveness of administering 13-valent pneumococcal conjugate vaccine in addition to 23-valent pneumococcal polysaccharide vaccine to adults with immunocompromising conditions</title><author>Cho, Bo-Hyun ; Stoecker, Charles ; Link-Gelles, Ruth ; Moore, Matthew R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c568t-aed99198cbaca4e1f0286bd7e6df459b77d1a53c59b0c0dec569ea55ca5745cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>Adult</topic><topic>adults</topic><topic>Aged</topic><topic>AIDS</topic><topic>Allergy and Immunology</topic><topic>Applied microbiology</topic><topic>Bacteriology</topic><topic>Biological and medical sciences</topic><topic>cost effectiveness</topic><topic>Cost-Benefit Analysis</topic><topic>disease incidence</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>HIV infections</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Immunization</topic><topic>Immunocompromised adults</topic><topic>Immunocompromised Host</topic><topic>immunocompromised population</topic><topic>Incremental cost-effectiveness</topic><topic>kidney diseases</topic><topic>Male</topic><topic>Microbiology</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Models, Statistical</topic><topic>Observational studies</topic><topic>organ transplantation</topic><topic>PCV13</topic><topic>Pneumococcal Infections - economics</topic><topic>Pneumococcal Infections - prevention & control</topic><topic>Pneumococcal Vaccines - administration & dosage</topic><topic>Pneumococcal Vaccines - economics</topic><topic>Pneumonia</topic><topic>probabilistic models</topic><topic>Public health</topic><topic>quality-adjusted life year</topic><topic>randomized clinical trials</topic><topic>risk</topic><topic>Streptococcus pneumoniae</topic><topic>Transplants & implants</topic><topic>United States</topic><topic>vaccination</topic><topic>Vaccination - 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subjects | Acquired immune deficiency syndrome Adult adults Aged AIDS Allergy and Immunology Applied microbiology Bacteriology Biological and medical sciences cost effectiveness Cost-Benefit Analysis disease incidence Female Fundamental and applied biological sciences. Psychology HIV infections Human immunodeficiency virus Humans Immunization Immunocompromised adults Immunocompromised Host immunocompromised population Incremental cost-effectiveness kidney diseases Male Microbiology Middle Aged Miscellaneous Models, Statistical Observational studies organ transplantation PCV13 Pneumococcal Infections - economics Pneumococcal Infections - prevention & control Pneumococcal Vaccines - administration & dosage Pneumococcal Vaccines - economics Pneumonia probabilistic models Public health quality-adjusted life year randomized clinical trials risk Streptococcus pneumoniae Transplants & implants United States vaccination Vaccination - economics Vaccination - methods Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Young Adult |
title | Cost-effectiveness of administering 13-valent pneumococcal conjugate vaccine in addition to 23-valent pneumococcal polysaccharide vaccine to adults with immunocompromising conditions |
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