EFA6A, a guanine nucleotide exchange factor for Arf6, interacts with sorting nexin‐1 and regulates neurite outgrowth

The membrane trafficking and actin cytoskeleton remodeling mediated by ADP ribosylation factor 6 (Arf6) are functionally linked to various neuronal processes including neurite formation and maintenance, neurotransmitter release, and receptor internalization. EFA6A is an Arf6‐specific guanine nucleot...

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Veröffentlicht in:	Journal of neurochemistry 2014-04, Vol.129 (1), p.21-36
Hauptverfasser:	Fukaya, Masahiro, Fukushima, Daisuke, Hara, Yoshinobu, Sakagami, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP ribosylation factor ADP-Ribosylation Factors - metabolism Animals Cells, Cultured Cytoskeleton dendritic spine guanine nucleotide exchange factor Guanine Nucleotide Exchange Factors - metabolism Guinea Pigs HeLa Cells Humans membrane traffic Mice Mice, Inbred C57BL Molecular Sequence Data Nerve Tissue Proteins - metabolism Neurites - physiology Neurites - ultrastructure Neurochemistry post‐synaptic density Protein Binding - physiology Rabbits Sorting Nexins - metabolism
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