EcVig, a novel grouper immune-gene associated with antiviral activity against NNV infection

•Four EcVig isoforms were isolated from orange-spotted grouper Epinephelus coioides, namely EcVig A–D.•EcVig is not involved in grouper response to Vibrio anguillarum challenge.•The expression level of EcVig showed significant up-regulation after nervous necrosis virus (NNV) challenge.•The overexpre...

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Veröffentlicht in:	Developmental and comparative immunology 2014-03, Vol.43 (1), p.68-75
Hauptverfasser:	Yeh, Ying-Chun, Hsu, Yi-Jiou, Chen, Yi-Min, Lin, Han-You, Yang, Huey-Lang, Chen, Tzong-Yueh, Wang, Han-Ching
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Animals Antiviral Agents - metabolism Brain - metabolism Brain - virology Cell Line Epinephelus coioides Fish Diseases - immunology Fish Proteins - genetics Fish Proteins - metabolism Fishes - immunology Fishes - virology Gene Expression Regulation Immunity Immunoglobulins - genetics Immunoglobulins - metabolism Nervous necrosis virus (NNV) Nodaviridae - physiology Oncorhynchus mykiss Orange-spotted grouper (Epinephelus coioides) Protein Isoforms - genetics Protein Structure, Tertiary - genetics RNA Virus Infections - immunology Sequence Homology, Amino Acid Transgenes - genetics VHSV induced gene (Vig) Vibrio - immunology Vibrio anguillarum Vibrio Infections - immunology Virus Replication
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