Demyelination and other neurological adverse events after anti-TNF therapy

Abstract Tumor necrosis factor (TNF) α inhibitors are an essential therapeutic option for several inflammatory diseases, like rheumatoid arthritis, spondyloarthropathies and inflammatory bowel diseases. As TNFα antagonists have become increasingly utilized, there have been a number of reports of neu...

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Veröffentlicht in:	Autoimmunity reviews 2014-01, Vol.13 (1), p.54-58
Hauptverfasser:	Kaltsonoudis, Evripidis, Voulgari, Paraskevi V, Konitsiotis, Spyridon, Drosos, Alexandros A
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Antibodies - adverse effects Antibodies - immunology Antibodies - therapeutic use Autoimmune Diseases - immunology Demyelinating Diseases - chemically induced Demyelinating Diseases - immunology Demyelinating Diseases - pathology Humans Multiple sclerosis Multiple Sclerosis - chemically induced Multiple Sclerosis - immunology Neurological adverse events sTNFα T-Lymphocytes - immunology tmTNFα TNFR1,2 TNFα antagonists Tumor Necrosis Factor-alpha - immunology
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