Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies

Abstract Carbamylation is a non-enzymatic post-translational modification in which cyanate binds to molecules containing primary amine or thiol groups and forms carbamyl groups. Cyanate is in equilibrium with urea in body fluid and increased carbamylation was first reported in patients with increase...

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Veröffentlicht in:	Autoimmunity reviews 2014-03, Vol.13 (3), p.225-230
Hauptverfasser:	Shi, Jing, van Veelen, Peter A, Mahler, Michael, Janssen, George M.C, Drijfhout, Jan W, Huizinga, Tom W.J, Toes, Rene E.M, Trouw, Leendert A
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Antibodies - immunology Autoimmunity - immunology Carbamates - immunology Carbamates - metabolism Humans Inflammation - immunology Protein Processing, Post-Translational Proteins - immunology
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