Rapid aldosterone actions on epithelial sodium channel trafficking and cell proliferation

Aldosterone regulates blood pressure through its effects on the kidney and the cardiovascular system. Dysregulation of aldosterone signalling can result in hypertension which in turn can lead to chronic pathologies of the kidney such as renal fibrosis and nephropathy. Aldosterone acts by binding to...

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Veröffentlicht in:	Steroids 2014-03, Vol.81, p.43-48
Hauptverfasser:	Quinn, Sinéad, Harvey, Brian J., Thomas, Warren
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone Aldosterone - physiology Cell Proliferation Epithelial sodium channel Epithelial Sodium Channels - metabolism Humans Kidney Kidney Tubules, Collecting - cytology Mitogen-Activated Protein Kinases - metabolism Protein Kinase C - metabolism Protein kinase D Protein Transport Receptor, Epidermal Growth Factor - metabolism Receptors, Mineralocorticoid - metabolism Signal Transduction
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