Vaspin inhibited proinflammatory cytokine induced activation of nuclear factor-kappa B and its downstream molecules in human endothelial EA.hy926 cells

Abstract Aims In this study, we investigated the effects of visceral adipose tissue-derived serpin (vaspin), a newly discovered adipocytokine, on nuclear factor-kappa B (NF-κB) and its downstream molecules in proinflammatory cytokines, tumor necrosis factor-α (TNF-α) and interleukine-1 (IL-1), stimu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Diabetes research and clinical practice 2014-03, Vol.103 (3), p.482-488
Hauptverfasser:	Liu, Shiwei, Dong, Yanting, Wang, Tong, Zhao, Shujun, Yang, Kun, Chen, Xiaoqin, Zheng, Caihong
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Cells, Cultured Chemokine CCL2 - genetics Chemokine CCL2 - metabolism Cytokines - pharmacology Endocrinology & Metabolism Endothelium Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Enzyme-Linked Immunosorbent Assay Humans Inflammation Inflammation - drug therapy Inflammation - genetics Inflammation - metabolism Insulin resistance Intercellular Adhesion Molecule-1 - genetics Intercellular Adhesion Molecule-1 - metabolism Interleukin-1 - pharmacology Interleukin-6 - pharmacology Luciferases - metabolism NF-kappa B - antagonists & inhibitors NF-kappa B - genetics NF-kappa B - metabolism NF-κB Real-Time Polymerase Chain Reaction RNA, Messenger - metabolism Serpins - pharmacology Tumor Necrosis Factor-alpha - pharmacology Vascular Cell Adhesion Molecule-1 - genetics Vascular Cell Adhesion Molecule-1 - metabolism Vaspin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!