Multi-drug resistance in cancer chemotherapeutics: Mechanisms and lab approaches

Abstract Multi-drug resistance (MDR) has become the largest obstacle to the success of cancer chemotherapies. The mechanisms of MDR and the approaches to test MDR have been discovered, yet not fully understood. This review covers the in vivo and in vitro approaches for the detection of MDR in the la...

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Veröffentlicht in:	Cancer letters 2014-06, Vol.347 (2), p.159-166
Hauptverfasser:	Wu, Qiong, Yang, Zhiping, Nie, Yongzhan, Shi, Yongquan, Fan, Daiming
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Apoptosis Autophagy Biomarker Breast cancer Cancer Chemotherapy Colleges & universities Drug Resistance, Multiple - genetics Drug Resistance, Multiple - immunology Drug Resistance, Neoplasm - genetics Drug Resistance, Neoplasm - immunology Epigenesis, Genetic Hematology, Oncology and Palliative Medicine Humans Lab approach Mechanism Medical research MicroRNAs - genetics Multi-drug resistance (MDR) Ovarian cancer
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