Rotavirus particles in the extrahepatic bile duct in experimental biliary atresia

Abstract Background Biliary atresia (BA) is the most common indication for liver transplantation in children. The experimental model of BA, induced by rotavirus infection in neonatal mice, has been widely used to investigate the inflammatory aspects of this disease. We investigated the kinetics and...

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Veröffentlicht in:	Journal of pediatric surgery 2014-04, Vol.49 (4), p.520-524
Hauptverfasser:	Oetzmann von Sochaczewski, Christina, Pintelon, Isabel, Brouns, Inge, Dreier, Anika, Klemann, Christian, Timmermans, Jean-Pierre, Petersen, Claus, Kuebler, Jochen Friedrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bile Ducts, Extrahepatic - virology Biliary atresia Biliary Atresia - virology Disease Models, Animal Extrahepatic bile duct Liver Mice Mice, Inbred BALB C Microscopy, Confocal Microscopy, Electron, Transmission Mouse model Obstruction Pediatrics Reverse Transcriptase Polymerase Chain Reaction RNA, Viral - analysis Rotavirus Rotavirus - genetics Rotavirus - isolation & purification Rotavirus Infections - complications Surgery Viral Load
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