Age-related changes in vasoactive intestinal polypeptide levels and distribution in the rat lung

Vasoactive intestinal polypeptide (VIP) levels and distribution were studied in the lung of young-adult (3-month-old) and aged (28-month-old) male Wistar rats by radioimmunoassay and immunofluorescence. VIP concentrations were reduced approximately by 60% as the animal ages. The density of VIP-immun...

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Veröffentlicht in:	Journal of Neural Transmission 1988-01, Vol.74 (1), p.1-10
Hauptverfasser:	GEPPETTI, P, DE ROSSI, M, MIONE, M. C, RENZI, D, AMENTA, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Air breathing Animals Biological and medical sciences Body Weight Fundamental and applied biological sciences. Psychology Immunohistochemistry Lung - blood supply Lung - growth & development Lung - innervation Male Muscle, Smooth - innervation Organ Size Pulmonary Artery - innervation Pulmonary Veins - innervation Rats Rats, Inbred Strains Respiratory system: anatomy, metabolism, gas exchange, ventilatory mechanics, respiratory hemodynamics Vasoactive Intestinal Peptide - metabolism Vasoactive Intestinal Peptide - physiology Vertebrates: respiratory system
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