Preparation and characterization of in-situ crosslinked pectin-gelatin hydrogels
Crosslinked hydrogels were developed by in-situ reaction of periodate oxidized pectin (OP) and gelatin. The reaction takes place through the formation of Schiff bases between aldehyde groups of OP and amino groups of gelatin. The effect of various process parameters such as reaction time, reaction t...
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| Veröffentlicht in: | Carbohydrate polymers 2014-06, Vol.106, p.312-318 |
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| creator | GUPTA, Bhuvanesh TUMMALAPALLI, Mythili DEOPURA, B. L ALAM, M. S |
| description | Crosslinked hydrogels were developed by in-situ reaction of periodate oxidized pectin (OP) and gelatin. The reaction takes place through the formation of Schiff bases between aldehyde groups of OP and amino groups of gelatin. The effect of various process parameters such as reaction time, reaction temperature, pH of the reaction and composition on the efficacy of the crosslinking was investigated. Field emission scanning electron micrsocopy (FESEM) revealed that homogenous, single phase systems are obtained after the crosslinking of OP and gelatin. The swelling characteristics of the hydrogels were monitored. The equilibrium swelling varies in the range of 195-324% with a variation in the gelatin content (10-40%). Glycerol, when used as a plasticizer, improved the flexibility and the handling characteristics of the crosslinked hydrogels. Plasticized films retained good tensile strengths in the range of 19-48 MPa. By proper selection of the reaction conditions, the efficiency of crosslinking can be controlled to obtain the optimum results. |
| doi_str_mv | 10.1016/j.carbpol.2014.02.019 |
| format | Article |
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Plasticized films retained good tensile strengths in the range of 19-48 MPa. 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L</creatorcontrib><creatorcontrib>ALAM, M. S</creatorcontrib><title>Preparation and characterization of in-situ crosslinked pectin-gelatin hydrogels</title><title>Carbohydrate polymers</title><addtitle>Carbohydr Polym</addtitle><description>Crosslinked hydrogels were developed by in-situ reaction of periodate oxidized pectin (OP) and gelatin. The reaction takes place through the formation of Schiff bases between aldehyde groups of OP and amino groups of gelatin. The effect of various process parameters such as reaction time, reaction temperature, pH of the reaction and composition on the efficacy of the crosslinking was investigated. Field emission scanning electron micrsocopy (FESEM) revealed that homogenous, single phase systems are obtained after the crosslinking of OP and gelatin. The swelling characteristics of the hydrogels were monitored. The equilibrium swelling varies in the range of 195-324% with a variation in the gelatin content (10-40%). Glycerol, when used as a plasticizer, improved the flexibility and the handling characteristics of the crosslinked hydrogels. Plasticized films retained good tensile strengths in the range of 19-48 MPa. By proper selection of the reaction conditions, the efficiency of crosslinking can be controlled to obtain the optimum results.</description><subject>Applied sciences</subject><subject>Biocompatible Materials - chemistry</subject><subject>Cross-Linking Reagents - chemistry</subject><subject>Exact sciences and technology</subject><subject>Gelatin - chemistry</subject><subject>Glycerol - chemistry</subject><subject>Hydrogels - chemistry</subject><subject>Hydrogen-Ion Concentration</subject><subject>Materials Testing</subject><subject>Microscopy, Electron, Scanning - methods</subject><subject>Natural polymers</subject><subject>Oxidation-Reduction</subject><subject>Pectins - chemistry</subject><subject>Periodic Acid - chemistry</subject><subject>Physicochemistry of polymers</subject><subject>Plasticizers - chemistry</subject><subject>Pliability</subject><subject>Proteins</subject><subject>Schiff Bases - chemical synthesis</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><subject>Starch and polysaccharides</subject><subject>Temperature</subject><subject>Tensile Strength</subject><subject>Viscosity</subject><issn>0144-8617</issn><issn>1879-1344</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtOwzAQRS0EoqXwCaBskNgkePxKskQVL6kSXcDacvygKWkS7HRRvh6XBvDGmuszM9ZB6BJwBhjE7TrTyld912QEA8swyTCUR2gKRV6mQBk7RtP4wNJCQD5BZyGscTwC8CmaEJYTwAWbouXS2155NdRdm6jWJHoVKz1YX38dws4ldZuGetgm2nchNHX7YU3SWz3E_N02EWuT1c74LhbhHJ041QR7Md4z9PZw_zp_Shcvj8_zu0WqKS2HlFPGRYFzUSpCgBIw1AitOcNcWJpTRnTlhBamLIhjUDpVGaUFFVw54wpFZ-jmMLf33efWhkFu6qBt06jWdtsggQMXrBCMR5Qf0J__e-tk7-uN8jsJWO5lyrUcZcq9TImJjDJj39W4YlttrPnr-rUXgesRUEGrxnnV6jr8cwUtCQdBvwE9_IA5</recordid><startdate>20140615</startdate><enddate>20140615</enddate><creator>GUPTA, Bhuvanesh</creator><creator>TUMMALAPALLI, Mythili</creator><creator>DEOPURA, B. 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S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c339t-5345680769a221321d3d6cc54056e37342cbf6c6d982f419fabdac6365afdf8a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Applied sciences</topic><topic>Biocompatible Materials - chemistry</topic><topic>Cross-Linking Reagents - chemistry</topic><topic>Exact sciences and technology</topic><topic>Gelatin - chemistry</topic><topic>Glycerol - chemistry</topic><topic>Hydrogels - chemistry</topic><topic>Hydrogen-Ion Concentration</topic><topic>Materials Testing</topic><topic>Microscopy, Electron, Scanning - methods</topic><topic>Natural polymers</topic><topic>Oxidation-Reduction</topic><topic>Pectins - chemistry</topic><topic>Periodic Acid - chemistry</topic><topic>Physicochemistry of polymers</topic><topic>Plasticizers - chemistry</topic><topic>Pliability</topic><topic>Proteins</topic><topic>Schiff Bases - chemical synthesis</topic><topic>Spectroscopy, Fourier Transform Infrared</topic><topic>Starch and polysaccharides</topic><topic>Temperature</topic><topic>Tensile Strength</topic><topic>Viscosity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>GUPTA, Bhuvanesh</creatorcontrib><creatorcontrib>TUMMALAPALLI, Mythili</creatorcontrib><creatorcontrib>DEOPURA, B. 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S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preparation and characterization of in-situ crosslinked pectin-gelatin hydrogels</atitle><jtitle>Carbohydrate polymers</jtitle><addtitle>Carbohydr Polym</addtitle><date>2014-06-15</date><risdate>2014</risdate><volume>106</volume><spage>312</spage><epage>318</epage><pages>312-318</pages><issn>0144-8617</issn><eissn>1879-1344</eissn><coden>CAPOD8</coden><abstract>Crosslinked hydrogels were developed by in-situ reaction of periodate oxidized pectin (OP) and gelatin. The reaction takes place through the formation of Schiff bases between aldehyde groups of OP and amino groups of gelatin. The effect of various process parameters such as reaction time, reaction temperature, pH of the reaction and composition on the efficacy of the crosslinking was investigated. Field emission scanning electron micrsocopy (FESEM) revealed that homogenous, single phase systems are obtained after the crosslinking of OP and gelatin. The swelling characteristics of the hydrogels were monitored. The equilibrium swelling varies in the range of 195-324% with a variation in the gelatin content (10-40%). Glycerol, when used as a plasticizer, improved the flexibility and the handling characteristics of the crosslinked hydrogels. Plasticized films retained good tensile strengths in the range of 19-48 MPa. By proper selection of the reaction conditions, the efficiency of crosslinking can be controlled to obtain the optimum results.</abstract><cop>Kidlington</cop><pub>Elsevier</pub><pmid>24721084</pmid><doi>10.1016/j.carbpol.2014.02.019</doi><tpages>7</tpages></addata></record> |
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| ispartof | Carbohydrate polymers, 2014-06, Vol.106, p.312-318 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Applied sciences Biocompatible Materials - chemistry Cross-Linking Reagents - chemistry Exact sciences and technology Gelatin - chemistry Glycerol - chemistry Hydrogels - chemistry Hydrogen-Ion Concentration Materials Testing Microscopy, Electron, Scanning - methods Natural polymers Oxidation-Reduction Pectins - chemistry Periodic Acid - chemistry Physicochemistry of polymers Plasticizers - chemistry Pliability Proteins Schiff Bases - chemical synthesis Spectroscopy, Fourier Transform Infrared Starch and polysaccharides Temperature Tensile Strength Viscosity |
| title | Preparation and characterization of in-situ crosslinked pectin-gelatin hydrogels |
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