Depth-enhanced 2-D optical coherence tomography using complex wavefront shaping

Depth-enhanced 2-D optical coherence tomography using complex wavefront shaping

We report the enhancement in the obtained signal and penetration depth of 2-D depth-resolved images that were taken by shaping the incident wavefront in optical coherence tomography (OCT). Limitations in the penetration depth and signal to noise ratio (SNR) in OCT are mainly due to multiple scatteri...

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Veröffentlicht in:Optics express 2014-04, Vol.22 (7), p.7514-7523
Hauptverfasser: Yu, Hyeonseung, Jang, Jaeduck, Lim, Jaeguyn, Park, Jung-Hoon, Jang, Wooyoung, Kim, Ji-Yeun, Park, YongKeun
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Sprache:eng
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Equipment Design
Humans
Image Enhancement - instrumentation
Phantoms, Imaging
Tomography, Optical Coherence - instrumentation
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container_end_page 7523
container_issue 7
container_start_page 7514
container_title Optics express
container_volume 22
creator Yu, Hyeonseung
Jang, Jaeduck
Lim, Jaeguyn
Park, Jung-Hoon
Jang, Wooyoung
Kim, Ji-Yeun
Park, YongKeun
description We report the enhancement in the obtained signal and penetration depth of 2-D depth-resolved images that were taken by shaping the incident wavefront in optical coherence tomography (OCT). Limitations in the penetration depth and signal to noise ratio (SNR) in OCT are mainly due to multiple scattering, which have been effectively suppressed by controlling the incident wavefront using a digital mirror device (DMD) in combination with spectral-domain OCT. The successful enhancements in the penetration depth and SNR are demonstrated in a wide-range of tissue phantoms, reaching depth enhancement of up to 92%. The hidden structures inside a tissue phantom that could not be seen in conventional OCT are clearly revealed through our proposed system. Its 2-D imaging capability, assisted by further optimization of the system for real-time acquisition speed will boost wide-spread use of OCT for in-vivo tissue diagnosis.
doi_str_mv 10.1364/OE.22.007514
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source MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Equipment Design
Humans
Image Enhancement - instrumentation
Phantoms, Imaging
Tomography, Optical Coherence - instrumentation
title Depth-enhanced 2-D optical coherence tomography using complex wavefront shaping
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