Endonasal resection of early stage squamous cell carcinoma of the nasal vestibule
The squamous cell carcinoma of the nasal vestibule (SCCNV) is a comparatively rare malignant disease. It occurs in the transition zone at the limen nasi. The choice of treatment for small tumors is a matter of controversy. Due to better cosmetic results, radiation therapy is usually recommended, how...
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Veröffentlicht in: | European archives of oto-rhino-laryngology 2014-05, Vol.271 (5), p.1051-1055 |
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description | The squamous cell carcinoma of the nasal vestibule (SCCNV) is a comparatively rare malignant disease. It occurs in the transition zone at the limen nasi. The choice of treatment for small tumors is a matter of controversy. Due to better cosmetic results, radiation therapy is usually recommended, however some recent reports have suggested that early stage tumors are equally or even more effectively managed by surgery. There was no standardized surgical procedure applied in these studies, though. The goal of our investigation was the retrospective evaluation of patients with a T1 or T2 carcinoma of the nasal vestibule who were treated surgically with an endonasal, endoscope-controlled approach at our ENT clinic between 2008 and 2010. Given the rarity of SCCNV, the 10 included cases represent the largest group of patients with early stage SCCNV treated primarily surgically by an endonasal approach so far. Our study shows that the endonasal resection of an early stage vestibular carcinoma seems adequate as a possible therapy. In the follow-up observation period no local or loco-regional recurrence was observed. The external cosmetic damage and endonasal scarring do not appear to be pronounced even following cartilage resection and were regarded as not seriously disadvantageous. |
doi_str_mv | 10.1007/s00405-013-2660-4 |
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It occurs in the transition zone at the limen nasi. The choice of treatment for small tumors is a matter of controversy. Due to better cosmetic results, radiation therapy is usually recommended, however some recent reports have suggested that early stage tumors are equally or even more effectively managed by surgery. There was no standardized surgical procedure applied in these studies, though. The goal of our investigation was the retrospective evaluation of patients with a T1 or T2 carcinoma of the nasal vestibule who were treated surgically with an endonasal, endoscope-controlled approach at our ENT clinic between 2008 and 2010. Given the rarity of SCCNV, the 10 included cases represent the largest group of patients with early stage SCCNV treated primarily surgically by an endonasal approach so far. Our study shows that the endonasal resection of an early stage vestibular carcinoma seems adequate as a possible therapy. In the follow-up observation period no local or loco-regional recurrence was observed. 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It occurs in the transition zone at the limen nasi. The choice of treatment for small tumors is a matter of controversy. Due to better cosmetic results, radiation therapy is usually recommended, however some recent reports have suggested that early stage tumors are equally or even more effectively managed by surgery. There was no standardized surgical procedure applied in these studies, though. The goal of our investigation was the retrospective evaluation of patients with a T1 or T2 carcinoma of the nasal vestibule who were treated surgically with an endonasal, endoscope-controlled approach at our ENT clinic between 2008 and 2010. Given the rarity of SCCNV, the 10 included cases represent the largest group of patients with early stage SCCNV treated primarily surgically by an endonasal approach so far. Our study shows that the endonasal resection of an early stage vestibular carcinoma seems adequate as a possible therapy. In the follow-up observation period no local or loco-regional recurrence was observed. The external cosmetic damage and endonasal scarring do not appear to be pronounced even following cartilage resection and were regarded as not seriously disadvantageous.</description><subject>Adult</subject><subject>Aged</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Cartilage - pathology</subject><subject>Cartilage - surgery</subject><subject>Cicatrix - diagnosis</subject><subject>Combined Modality Therapy</subject><subject>Endoscopy</subject><subject>Esthetics</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Head and Neck Surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nasal Cavity - pathology</subject><subject>Nasal Cavity - surgery</subject><subject>Neoplasm Staging</subject><subject>Neurosurgery</subject><subject>Nose Neoplasms - pathology</subject><subject>Nose Neoplasms - surgery</subject><subject>Otorhinolaryngology</subject><subject>Postoperative Complications - diagnosis</subject><subject>Radiotherapy, Adjuvant</subject><subject>Rhinology</subject><subject>Tomography, X-Ray Computed</subject><issn>0937-4477</issn><issn>1434-4726</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDtPwzAYRS0EoqXwA1iQR5aAH1_iekQVL6kSQupuOX6UVHm0doLUf4-jFEYmDz73-vogdEvJAyVEPEZCgOQZoTxjRUEyOENzChwyEKw4R3MiucgAhJihqxh3hJAcJL9EM8alAM7ZHH0-t7ZrddQ1Di4601ddizuPnQ71Ecdebx2Oh0E33RCxcXWNjQ6martGj1j_5fCU_naxr8qhdtfowus6upvTuUCbl-fN6i1bf7y-r57WmeEAfVYIyEsCy9ILa3MLS1t6SQsmDXPEp6WFWHIQUnoviPCl0cwYZiXNhXV2yRfofqrdh-4wpMdVU8VxoG5d2qpoTiGpYHmRUDqhJnQxBufVPlSNDkdFiRpFqkmkSiLVKFJBytyd6oeycfYv8WsuAWwCYrpqty6oXTeENv34n9YfKCh-Nw</recordid><startdate>20140501</startdate><enddate>20140501</enddate><creator>Ledderose, Georg J.</creator><creator>Reu, Simone</creator><creator>Englhard, Anna S.</creator><creator>Krause, Eike</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140501</creationdate><title>Endonasal resection of early stage squamous cell carcinoma of the nasal vestibule</title><author>Ledderose, Georg J. ; Reu, Simone ; Englhard, Anna S. ; Krause, Eike</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c344t-6745b048bf7dd5d48dbf91629c2e0f00567834799ff707fbca2cc2d9157ded83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Cartilage - pathology</topic><topic>Cartilage - surgery</topic><topic>Cicatrix - diagnosis</topic><topic>Combined Modality Therapy</topic><topic>Endoscopy</topic><topic>Esthetics</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Head and Neck Surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nasal Cavity - pathology</topic><topic>Nasal Cavity - surgery</topic><topic>Neoplasm Staging</topic><topic>Neurosurgery</topic><topic>Nose Neoplasms - pathology</topic><topic>Nose Neoplasms - surgery</topic><topic>Otorhinolaryngology</topic><topic>Postoperative Complications - diagnosis</topic><topic>Radiotherapy, Adjuvant</topic><topic>Rhinology</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ledderose, Georg J.</creatorcontrib><creatorcontrib>Reu, Simone</creatorcontrib><creatorcontrib>Englhard, Anna S.</creatorcontrib><creatorcontrib>Krause, Eike</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European archives of oto-rhino-laryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ledderose, Georg J.</au><au>Reu, Simone</au><au>Englhard, Anna S.</au><au>Krause, Eike</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endonasal resection of early stage squamous cell carcinoma of the nasal vestibule</atitle><jtitle>European archives of oto-rhino-laryngology</jtitle><stitle>Eur Arch Otorhinolaryngol</stitle><addtitle>Eur Arch Otorhinolaryngol</addtitle><date>2014-05-01</date><risdate>2014</risdate><volume>271</volume><issue>5</issue><spage>1051</spage><epage>1055</epage><pages>1051-1055</pages><issn>0937-4477</issn><eissn>1434-4726</eissn><abstract>The squamous cell carcinoma of the nasal vestibule (SCCNV) is a comparatively rare malignant disease. It occurs in the transition zone at the limen nasi. The choice of treatment for small tumors is a matter of controversy. Due to better cosmetic results, radiation therapy is usually recommended, however some recent reports have suggested that early stage tumors are equally or even more effectively managed by surgery. There was no standardized surgical procedure applied in these studies, though. The goal of our investigation was the retrospective evaluation of patients with a T1 or T2 carcinoma of the nasal vestibule who were treated surgically with an endonasal, endoscope-controlled approach at our ENT clinic between 2008 and 2010. Given the rarity of SCCNV, the 10 included cases represent the largest group of patients with early stage SCCNV treated primarily surgically by an endonasal approach so far. Our study shows that the endonasal resection of an early stage vestibular carcinoma seems adequate as a possible therapy. 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subjects | Adult Aged Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Cartilage - pathology Cartilage - surgery Cicatrix - diagnosis Combined Modality Therapy Endoscopy Esthetics Female Follow-Up Studies Head and Neck Surgery Humans Male Medicine Medicine & Public Health Middle Aged Nasal Cavity - pathology Nasal Cavity - surgery Neoplasm Staging Neurosurgery Nose Neoplasms - pathology Nose Neoplasms - surgery Otorhinolaryngology Postoperative Complications - diagnosis Radiotherapy, Adjuvant Rhinology Tomography, X-Ray Computed |
title | Endonasal resection of early stage squamous cell carcinoma of the nasal vestibule |
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