JAK2V617F allele burden in patients with myeloproliferative neoplasms

Myeloproliferative neoplasms (MPNs) are clonal malignant diseases that represent a group of conditions including polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF). The JAK2-V617F mutation is prevalent in almost all patients with MPNs and has become a valuable biomarker f...

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Veröffentlicht in:	Annals of hematology 2014-05, Vol.93 (5), p.791-796
Hauptverfasser:	Alshemmari, Salem H., Rajaan, Reshmi, Ameen, Reem, Al-Drees, Mohammad A., Almosailleakh, Marwa R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biomarkers - metabolism Gene Frequency Genotype Hematology Humans Janus Kinase 2 - genetics Medicine Medicine & Public Health Mutation Oncology Original Article Phenotype Polycythemia Vera - diagnosis Polycythemia Vera - genetics Primary Myelofibrosis - diagnosis Primary Myelofibrosis - genetics Real-Time Polymerase Chain Reaction Thrombocythemia, Essential - diagnosis Thrombocythemia, Essential - genetics
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