Somatostatin analogs: does pharmacology impact antitumor efficacy?

Highlights • Novel multireceptor somatostatin analogs may putatively present higher antitumor activities. • Biased agonism indicates that different somatostatin analogs cannot be considered as simple mimics of the native somatostatins. • Pharmacologic differences in somatostatin analogs need to be t...

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Veröffentlicht in:	Trends in endocrinology and metabolism 2014-03, Vol.25 (3), p.115-127
Hauptverfasser:	Chalabi, Mounira, Duluc, Camille, Caron, Philippe, Vezzosi, Delphine, Guillermet-Guibert, Julie, Pyronnet, Stéphane, Bousquet, Corinne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antitumor efficacy biased agonism Cell Proliferation Endocrinology & Metabolism Humans neuroendocrine tumors Neuroendocrine Tumors - drug therapy pharmacotherapy Somatostatin - analogs & derivatives Somatostatin - therapeutic use somatostatin analogs
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