Mechanical properties of cancer cytoskeleton depend on actin filaments to microtubules content: Investigating different grades of colon cancer cell lines

Abstract Biomechanical properties of cancer cells have been proposed as promising biomarkers to investigate cancer progression. Cytoskeletal reorganization alters these characteristics in different grades of cancer cells. In the present study based on the micropipette aspiration method, whole body e...

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Veröffentlicht in:	Journal of biomechanics 2014-01, Vol.47 (2), p.373-379
Hauptverfasser:	Pachenari, M, Seyedpour, S.M, Janmaleki, M, Shayan, S. Babazadeh, Taranejoo, S, Hosseinkhani, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Actin Cytoskeleton - metabolism Actins - metabolism Albendazole - pharmacology Biomechanics Blotting, Western Cancer Cancer cell mechanics Cell Movement - drug effects Colon Colonic Neoplasms - pathology Colorectal cancer Cytoskeleton Cytoskeleton - pathology Elastic Modulus - physiology Elasticity Filaments Finite Element Analysis HT29 Cells Humans Mathematical models Medical research Micropipette aspiration Microtubules - metabolism Microtubules - pathology Networks Physical Medicine and Rehabilitation Rate of deformability Sorting Viscosity
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