A prospective multicenter clinical trial of extralevator abdominoperineal excision for locally advanced low rectal cancer
To demonstrate the feasibility of extralevator abdominoperineal excision (ELAPE) for locally advanced low cancer in China. A prospective multicenter clinical trial was carried out by 7 general hospitals across China from August 2008 to October 2011. A total of 102 patients underwent ELAPE for primar...
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| Veröffentlicht in: | Chung-hua wai kʿo tsa chih 2014-01, Vol.52 (1), p.11-15 |
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| container_title | Chung-hua wai kʿo tsa chih |
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| creator | Wang, Zhenjun Qian, Qun Dai, Yong Zhang, Zhiquan Yang, Jinshan Li, Fei Li, Xiaobin Han, Jiagang Jiang, Congqing Jiang, Jinbo Qi, Baoju Liu, Zuojun Gao, Zhigang Du, Yanfu Yang, Yong Wei, Guanghui Qu, Hao Li, Minzhe Ma, Huachong Yi, Bingqiang |
| description | To demonstrate the feasibility of extralevator abdominoperineal excision (ELAPE) for locally advanced low cancer in China.
A prospective multicenter clinical trial was carried out by 7 general hospitals across China from August 2008 to October 2011. A total of 102 patients underwent ELAPE for primary locally advanced low rectal cancer. There were 60 male and 42 female patients. The patients' characteristics, complications and prognosis were recorded.
All patients underwent the ELAPE procedure successfully. The median operating time was 180 minutes (range 110-495 minutes) and median intraoperative blood loss was 200 ml (range 50-1000 ml). The rates of sexual dysfunction, perineal complications, urinary retention, and chronic perineal pain were 40.5%, 23.5%, 18.6% and 13.7%, respectively. Chronic perineal pain was associated with coccygectomy (12 months postoperatively, t = 8.06, P < 0.01), and the pain might gradually ease over time. Reconstruction of pelvic floor with biologic mesh was associated with lower r |
| format | Article |
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A prospective multicenter clinical trial was carried out by 7 general hospitals across China from August 2008 to October 2011. A total of 102 patients underwent ELAPE for primary locally advanced low rectal cancer. There were 60 male and 42 female patients. The patients' characteristics, complications and prognosis were recorded.
All patients underwent the ELAPE procedure successfully. The median operating time was 180 minutes (range 110-495 minutes) and median intraoperative blood loss was 200 ml (range 50-1000 ml). The rates of sexual dysfunction, perineal complications, urinary retention, and chronic perineal pain were 40.5%, 23.5%, 18.6% and 13.7%, respectively. Chronic perineal pain was associated with coccygectomy (12 months postoperatively, t = 8.06, P < 0.01), and the pain might gradually ease over time. Reconstruction of pelvic floor with biologic mesh was associated with lower r</description><identifier>ISSN: 0529-5815</identifier><identifier>PMID: 24697933</identifier><language>chi</language><publisher>China</publisher><subject>Adult ; Aged ; Digestive System Surgical Procedures - methods ; Female ; Humans ; Male ; Middle Aged ; Perineum - surgery ; Postoperative Complications ; Prognosis ; Prospective Studies ; Rectal Neoplasms - surgery ; Treatment Outcome</subject><ispartof>Chung-hua wai kʿo tsa chih, 2014-01, Vol.52 (1), p.11-15</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24697933$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Zhenjun</creatorcontrib><creatorcontrib>Qian, Qun</creatorcontrib><creatorcontrib>Dai, Yong</creatorcontrib><creatorcontrib>Zhang, Zhiquan</creatorcontrib><creatorcontrib>Yang, Jinshan</creatorcontrib><creatorcontrib>Li, Fei</creatorcontrib><creatorcontrib>Li, Xiaobin</creatorcontrib><creatorcontrib>Han, Jiagang</creatorcontrib><creatorcontrib>Jiang, Congqing</creatorcontrib><creatorcontrib>Jiang, Jinbo</creatorcontrib><creatorcontrib>Qi, Baoju</creatorcontrib><creatorcontrib>Liu, Zuojun</creatorcontrib><creatorcontrib>Gao, Zhigang</creatorcontrib><creatorcontrib>Du, Yanfu</creatorcontrib><creatorcontrib>Yang, Yong</creatorcontrib><creatorcontrib>Wei, Guanghui</creatorcontrib><creatorcontrib>Qu, Hao</creatorcontrib><creatorcontrib>Li, Minzhe</creatorcontrib><creatorcontrib>Ma, Huachong</creatorcontrib><creatorcontrib>Yi, Bingqiang</creatorcontrib><title>A prospective multicenter clinical trial of extralevator abdominoperineal excision for locally advanced low rectal cancer</title><title>Chung-hua wai kʿo tsa chih</title><addtitle>Zhonghua Wai Ke Za Zhi</addtitle><description>To demonstrate the feasibility of extralevator abdominoperineal excision (ELAPE) for locally advanced low cancer in China.
A prospective multicenter clinical trial was carried out by 7 general hospitals across China from August 2008 to October 2011. A total of 102 patients underwent ELAPE for primary locally advanced low rectal cancer. There were 60 male and 42 female patients. The patients' characteristics, complications and prognosis were recorded.
All patients underwent the ELAPE procedure successfully. The median operating time was 180 minutes (range 110-495 minutes) and median intraoperative blood loss was 200 ml (range 50-1000 ml). The rates of sexual dysfunction, perineal complications, urinary retention, and chronic perineal pain were 40.5%, 23.5%, 18.6% and 13.7%, respectively. Chronic perineal pain was associated with coccygectomy (12 months postoperatively, t = 8.06, P < 0.01), and the pain might gradually ease over time. Reconstruction of pelvic floor with biologic mesh was associated with lower r</description><subject>Adult</subject><subject>Aged</subject><subject>Digestive System Surgical Procedures - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Perineum - surgery</subject><subject>Postoperative Complications</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Rectal Neoplasms - surgery</subject><subject>Treatment Outcome</subject><issn>0529-5815</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kE1LAzEQhnNQbK3-BcnRy0KSTfbjWIpfUPCi5yWdzEIkm6xJtrb_3oh6mYF3nndeZi7IminRV6rjakWuU_pgTAqmmiuyErLp276u1-S8pXMMaUbI9oh0Wly2gD5jpOCst6AdzdGWGkaKpxy1w6POIVJ9MGGyPswYrccC4AlsssHTsUxdKE53ptoctQc0RfiisaQUEH6UeEMuR-0S3v71DXl_fHjbPVf716eX3XZfzVw0uWo5NLIHxrXoQUArO8V5A20nUBg5AiKDkclGa2WMOLBOYnEgZ7zlI_K-3pD7373lzs8FUx4mmwCd0x7DkgaueM1U20lV0Ls_dDlMaIY52knH8_D_rvobnTxobA</recordid><startdate>201401</startdate><enddate>201401</enddate><creator>Wang, Zhenjun</creator><creator>Qian, Qun</creator><creator>Dai, Yong</creator><creator>Zhang, Zhiquan</creator><creator>Yang, Jinshan</creator><creator>Li, Fei</creator><creator>Li, Xiaobin</creator><creator>Han, Jiagang</creator><creator>Jiang, Congqing</creator><creator>Jiang, Jinbo</creator><creator>Qi, Baoju</creator><creator>Liu, Zuojun</creator><creator>Gao, Zhigang</creator><creator>Du, Yanfu</creator><creator>Yang, Yong</creator><creator>Wei, Guanghui</creator><creator>Qu, Hao</creator><creator>Li, Minzhe</creator><creator>Ma, Huachong</creator><creator>Yi, Bingqiang</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201401</creationdate><title>A prospective multicenter clinical trial of extralevator abdominoperineal excision for locally advanced low rectal cancer</title><author>Wang, Zhenjun ; 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A prospective multicenter clinical trial was carried out by 7 general hospitals across China from August 2008 to October 2011. A total of 102 patients underwent ELAPE for primary locally advanced low rectal cancer. There were 60 male and 42 female patients. The patients' characteristics, complications and prognosis were recorded.
All patients underwent the ELAPE procedure successfully. The median operating time was 180 minutes (range 110-495 minutes) and median intraoperative blood loss was 200 ml (range 50-1000 ml). The rates of sexual dysfunction, perineal complications, urinary retention, and chronic perineal pain were 40.5%, 23.5%, 18.6% and 13.7%, respectively. Chronic perineal pain was associated with coccygectomy (12 months postoperatively, t = 8.06, P < 0.01), and the pain might gradually ease over time. Reconstruction of pelvic floor with biologic mesh was associated with lower r</abstract><cop>China</cop><pmid>24697933</pmid><tpages>5</tpages></addata></record> |
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| subjects | Adult Aged Digestive System Surgical Procedures - methods Female Humans Male Middle Aged Perineum - surgery Postoperative Complications Prognosis Prospective Studies Rectal Neoplasms - surgery Treatment Outcome |
| title | A prospective multicenter clinical trial of extralevator abdominoperineal excision for locally advanced low rectal cancer |
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