Massive perivillous fibrin deposition in the placenta and uterine metastasis of gastric adenocarcinoma during pregnancy
The prognosis of gastric cancer during pregnancy is unfavorable because of delayed diagnosis and advanced stage. We present a case of gastric carcinoma metastasized to the placenta and uterus during pregnancy. Pathological examination revealed a poorly differentiated adenocarcinoma of the stomach wi...
Gespeichert in:
| Veröffentlicht in: | The journal of obstetrics and gynaecology research 2014-04, Vol.40 (4), p.1150-1153 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1153 |
|---|---|
| container_issue | 4 |
| container_start_page | 1150 |
| container_title | The journal of obstetrics and gynaecology research |
| container_volume | 40 |
| creator | Jeong, Bada Shim, Jae‐Yoon Kim, Chong Jai Won, Hye‐Sung Lee, Pil Ryang Kim, Ahm |
| description | The prognosis of gastric cancer during pregnancy is unfavorable because of delayed diagnosis and advanced stage. We present a case of gastric carcinoma metastasized to the placenta and uterus during pregnancy. Pathological examination revealed a poorly differentiated adenocarcinoma of the stomach with lymph node metastasis. After counseling, the patient decided to terminate the pregnancy and begin immediate treatment for gastric cancer. Hysterectomy and subtotal hysterectomy were performed because medical termination of the pregnancy was unsuccessful. Pathological examination of the placenta and uterus revealed metastases of gastric adenocarcinoma. All the uterine vessels were packed with tumor cells and the myometrium showed extensive coagulative necrosis. Moreover, microscopic findings of the placenta were consistent with massive perivillous fibrin deposition. Our case clearly suggests that massive perivillous fibrin deposition in the placenta can be associated with malignancy during pregnancy and that uterine metastasis of maternal malignancy may result in myometrial dysfunction unresponsive to uterotonics. |
| doi_str_mv | 10.1111/jog.12292 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1513051499</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1513051499</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4152-25802deb2a3a7496752f896dc327d9f4928cb2b0b6322f875532037691f9d3c23</originalsourceid><addsrcrecordid>eNp1kMtOwzAQRS0EouWx4AeQl7BI8StxvEQVTxWxgXXk2E5xldjBTlr17zG0sGM00sxozlxpLgAXGM1wipuVX84wIYIcgClmjGeI58Vh6inDWYl4MQEnMa4Qwlzg8hhMCGOk5FxMweZFxmjXBvYm2LVtWz9G2Ng6WAe16X20g_UOpmn4SFArlXGDhNJpOA7pxBnYmUHGlDZC38Bl6oNVUGrjvJJBWec7CfWY2CXsg1k66dT2DBw1so3mfF9Pwfv93dv8MVu8PjzNbxeZYjgnGclLRLSpiaSSM1HwnDSlKLSihGvRMEFKVZMa1QUlacPznBJEeSFwIzRVhJ6Cq51uH_znaOJQdTYq07bSmfRqhXNMUY6ZEAm93qEq-BiDaao-2E6GbYVR9e1zlXyufnxO7OVedqw7o__IX2MTcLMDNrY12_-VqufXh53kF3R8iKc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1513051499</pqid></control><display><type>article</type><title>Massive perivillous fibrin deposition in the placenta and uterine metastasis of gastric adenocarcinoma during pregnancy</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Jeong, Bada ; Shim, Jae‐Yoon ; Kim, Chong Jai ; Won, Hye‐Sung ; Lee, Pil Ryang ; Kim, Ahm</creator><creatorcontrib>Jeong, Bada ; Shim, Jae‐Yoon ; Kim, Chong Jai ; Won, Hye‐Sung ; Lee, Pil Ryang ; Kim, Ahm</creatorcontrib><description>The prognosis of gastric cancer during pregnancy is unfavorable because of delayed diagnosis and advanced stage. We present a case of gastric carcinoma metastasized to the placenta and uterus during pregnancy. Pathological examination revealed a poorly differentiated adenocarcinoma of the stomach with lymph node metastasis. After counseling, the patient decided to terminate the pregnancy and begin immediate treatment for gastric cancer. Hysterectomy and subtotal hysterectomy were performed because medical termination of the pregnancy was unsuccessful. Pathological examination of the placenta and uterus revealed metastases of gastric adenocarcinoma. All the uterine vessels were packed with tumor cells and the myometrium showed extensive coagulative necrosis. Moreover, microscopic findings of the placenta were consistent with massive perivillous fibrin deposition. Our case clearly suggests that massive perivillous fibrin deposition in the placenta can be associated with malignancy during pregnancy and that uterine metastasis of maternal malignancy may result in myometrial dysfunction unresponsive to uterotonics.</description><identifier>ISSN: 1341-8076</identifier><identifier>EISSN: 1447-0756</identifier><identifier>DOI: 10.1111/jog.12292</identifier><identifier>PMID: 24428779</identifier><language>eng</language><publisher>Australia</publisher><subject>Adenocarcinoma - blood supply ; Adenocarcinoma - metabolism ; Adenocarcinoma - pathology ; Adenocarcinoma - secondary ; Adult ; Chorionic Villi - blood supply ; Chorionic Villi - metabolism ; Chorionic Villi - pathology ; Female ; Fibrin - metabolism ; gastric cancer ; Humans ; metastasis ; Necrosis ; Neoplasm Proteins - metabolism ; perivillous fibrin deposition ; Placenta - blood supply ; Placenta - metabolism ; Placenta - pathology ; Placental Circulation ; Pregnancy ; Stomach Neoplasms - metabolism ; Stomach Neoplasms - pathology ; Trophoblastic Tumor, Placental Site - blood supply ; Trophoblastic Tumor, Placental Site - metabolism ; Trophoblastic Tumor, Placental Site - pathology ; Trophoblastic Tumor, Placental Site - secondary ; Up-Regulation ; Uterine Neoplasms - blood supply ; Uterine Neoplasms - metabolism ; Uterine Neoplasms - pathology ; Uterine Neoplasms - secondary ; Uterus - blood supply ; Uterus - metabolism ; Uterus - pathology</subject><ispartof>The journal of obstetrics and gynaecology research, 2014-04, Vol.40 (4), p.1150-1153</ispartof><rights>2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology</rights><rights>2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4152-25802deb2a3a7496752f896dc327d9f4928cb2b0b6322f875532037691f9d3c23</citedby><cites>FETCH-LOGICAL-c4152-25802deb2a3a7496752f896dc327d9f4928cb2b0b6322f875532037691f9d3c23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjog.12292$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjog.12292$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24428779$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jeong, Bada</creatorcontrib><creatorcontrib>Shim, Jae‐Yoon</creatorcontrib><creatorcontrib>Kim, Chong Jai</creatorcontrib><creatorcontrib>Won, Hye‐Sung</creatorcontrib><creatorcontrib>Lee, Pil Ryang</creatorcontrib><creatorcontrib>Kim, Ahm</creatorcontrib><title>Massive perivillous fibrin deposition in the placenta and uterine metastasis of gastric adenocarcinoma during pregnancy</title><title>The journal of obstetrics and gynaecology research</title><addtitle>J Obstet Gynaecol Res</addtitle><description>The prognosis of gastric cancer during pregnancy is unfavorable because of delayed diagnosis and advanced stage. We present a case of gastric carcinoma metastasized to the placenta and uterus during pregnancy. Pathological examination revealed a poorly differentiated adenocarcinoma of the stomach with lymph node metastasis. After counseling, the patient decided to terminate the pregnancy and begin immediate treatment for gastric cancer. Hysterectomy and subtotal hysterectomy were performed because medical termination of the pregnancy was unsuccessful. Pathological examination of the placenta and uterus revealed metastases of gastric adenocarcinoma. All the uterine vessels were packed with tumor cells and the myometrium showed extensive coagulative necrosis. Moreover, microscopic findings of the placenta were consistent with massive perivillous fibrin deposition. Our case clearly suggests that massive perivillous fibrin deposition in the placenta can be associated with malignancy during pregnancy and that uterine metastasis of maternal malignancy may result in myometrial dysfunction unresponsive to uterotonics.</description><subject>Adenocarcinoma - blood supply</subject><subject>Adenocarcinoma - metabolism</subject><subject>Adenocarcinoma - pathology</subject><subject>Adenocarcinoma - secondary</subject><subject>Adult</subject><subject>Chorionic Villi - blood supply</subject><subject>Chorionic Villi - metabolism</subject><subject>Chorionic Villi - pathology</subject><subject>Female</subject><subject>Fibrin - metabolism</subject><subject>gastric cancer</subject><subject>Humans</subject><subject>metastasis</subject><subject>Necrosis</subject><subject>Neoplasm Proteins - metabolism</subject><subject>perivillous fibrin deposition</subject><subject>Placenta - blood supply</subject><subject>Placenta - metabolism</subject><subject>Placenta - pathology</subject><subject>Placental Circulation</subject><subject>Pregnancy</subject><subject>Stomach Neoplasms - metabolism</subject><subject>Stomach Neoplasms - pathology</subject><subject>Trophoblastic Tumor, Placental Site - blood supply</subject><subject>Trophoblastic Tumor, Placental Site - metabolism</subject><subject>Trophoblastic Tumor, Placental Site - pathology</subject><subject>Trophoblastic Tumor, Placental Site - secondary</subject><subject>Up-Regulation</subject><subject>Uterine Neoplasms - blood supply</subject><subject>Uterine Neoplasms - metabolism</subject><subject>Uterine Neoplasms - pathology</subject><subject>Uterine Neoplasms - secondary</subject><subject>Uterus - blood supply</subject><subject>Uterus - metabolism</subject><subject>Uterus - pathology</subject><issn>1341-8076</issn><issn>1447-0756</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMtOwzAQRS0EouWx4AeQl7BI8StxvEQVTxWxgXXk2E5xldjBTlr17zG0sGM00sxozlxpLgAXGM1wipuVX84wIYIcgClmjGeI58Vh6inDWYl4MQEnMa4Qwlzg8hhMCGOk5FxMweZFxmjXBvYm2LVtWz9G2Ng6WAe16X20g_UOpmn4SFArlXGDhNJpOA7pxBnYmUHGlDZC38Bl6oNVUGrjvJJBWec7CfWY2CXsg1k66dT2DBw1so3mfF9Pwfv93dv8MVu8PjzNbxeZYjgnGclLRLSpiaSSM1HwnDSlKLSihGvRMEFKVZMa1QUlacPznBJEeSFwIzRVhJ6Cq51uH_znaOJQdTYq07bSmfRqhXNMUY6ZEAm93qEq-BiDaao-2E6GbYVR9e1zlXyufnxO7OVedqw7o__IX2MTcLMDNrY12_-VqufXh53kF3R8iKc</recordid><startdate>201404</startdate><enddate>201404</enddate><creator>Jeong, Bada</creator><creator>Shim, Jae‐Yoon</creator><creator>Kim, Chong Jai</creator><creator>Won, Hye‐Sung</creator><creator>Lee, Pil Ryang</creator><creator>Kim, Ahm</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201404</creationdate><title>Massive perivillous fibrin deposition in the placenta and uterine metastasis of gastric adenocarcinoma during pregnancy</title><author>Jeong, Bada ; Shim, Jae‐Yoon ; Kim, Chong Jai ; Won, Hye‐Sung ; Lee, Pil Ryang ; Kim, Ahm</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4152-25802deb2a3a7496752f896dc327d9f4928cb2b0b6322f875532037691f9d3c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adenocarcinoma - blood supply</topic><topic>Adenocarcinoma - metabolism</topic><topic>Adenocarcinoma - pathology</topic><topic>Adenocarcinoma - secondary</topic><topic>Adult</topic><topic>Chorionic Villi - blood supply</topic><topic>Chorionic Villi - metabolism</topic><topic>Chorionic Villi - pathology</topic><topic>Female</topic><topic>Fibrin - metabolism</topic><topic>gastric cancer</topic><topic>Humans</topic><topic>metastasis</topic><topic>Necrosis</topic><topic>Neoplasm Proteins - metabolism</topic><topic>perivillous fibrin deposition</topic><topic>Placenta - blood supply</topic><topic>Placenta - metabolism</topic><topic>Placenta - pathology</topic><topic>Placental Circulation</topic><topic>Pregnancy</topic><topic>Stomach Neoplasms - metabolism</topic><topic>Stomach Neoplasms - pathology</topic><topic>Trophoblastic Tumor, Placental Site - blood supply</topic><topic>Trophoblastic Tumor, Placental Site - metabolism</topic><topic>Trophoblastic Tumor, Placental Site - pathology</topic><topic>Trophoblastic Tumor, Placental Site - secondary</topic><topic>Up-Regulation</topic><topic>Uterine Neoplasms - blood supply</topic><topic>Uterine Neoplasms - metabolism</topic><topic>Uterine Neoplasms - pathology</topic><topic>Uterine Neoplasms - secondary</topic><topic>Uterus - blood supply</topic><topic>Uterus - metabolism</topic><topic>Uterus - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jeong, Bada</creatorcontrib><creatorcontrib>Shim, Jae‐Yoon</creatorcontrib><creatorcontrib>Kim, Chong Jai</creatorcontrib><creatorcontrib>Won, Hye‐Sung</creatorcontrib><creatorcontrib>Lee, Pil Ryang</creatorcontrib><creatorcontrib>Kim, Ahm</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of obstetrics and gynaecology research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jeong, Bada</au><au>Shim, Jae‐Yoon</au><au>Kim, Chong Jai</au><au>Won, Hye‐Sung</au><au>Lee, Pil Ryang</au><au>Kim, Ahm</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Massive perivillous fibrin deposition in the placenta and uterine metastasis of gastric adenocarcinoma during pregnancy</atitle><jtitle>The journal of obstetrics and gynaecology research</jtitle><addtitle>J Obstet Gynaecol Res</addtitle><date>2014-04</date><risdate>2014</risdate><volume>40</volume><issue>4</issue><spage>1150</spage><epage>1153</epage><pages>1150-1153</pages><issn>1341-8076</issn><eissn>1447-0756</eissn><abstract>The prognosis of gastric cancer during pregnancy is unfavorable because of delayed diagnosis and advanced stage. We present a case of gastric carcinoma metastasized to the placenta and uterus during pregnancy. Pathological examination revealed a poorly differentiated adenocarcinoma of the stomach with lymph node metastasis. After counseling, the patient decided to terminate the pregnancy and begin immediate treatment for gastric cancer. Hysterectomy and subtotal hysterectomy were performed because medical termination of the pregnancy was unsuccessful. Pathological examination of the placenta and uterus revealed metastases of gastric adenocarcinoma. All the uterine vessels were packed with tumor cells and the myometrium showed extensive coagulative necrosis. Moreover, microscopic findings of the placenta were consistent with massive perivillous fibrin deposition. Our case clearly suggests that massive perivillous fibrin deposition in the placenta can be associated with malignancy during pregnancy and that uterine metastasis of maternal malignancy may result in myometrial dysfunction unresponsive to uterotonics.</abstract><cop>Australia</cop><pmid>24428779</pmid><doi>10.1111/jog.12292</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1341-8076 |
| ispartof | The journal of obstetrics and gynaecology research, 2014-04, Vol.40 (4), p.1150-1153 |
| issn | 1341-8076 1447-0756 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1513051499 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adenocarcinoma - blood supply Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenocarcinoma - secondary Adult Chorionic Villi - blood supply Chorionic Villi - metabolism Chorionic Villi - pathology Female Fibrin - metabolism gastric cancer Humans metastasis Necrosis Neoplasm Proteins - metabolism perivillous fibrin deposition Placenta - blood supply Placenta - metabolism Placenta - pathology Placental Circulation Pregnancy Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Trophoblastic Tumor, Placental Site - blood supply Trophoblastic Tumor, Placental Site - metabolism Trophoblastic Tumor, Placental Site - pathology Trophoblastic Tumor, Placental Site - secondary Up-Regulation Uterine Neoplasms - blood supply Uterine Neoplasms - metabolism Uterine Neoplasms - pathology Uterine Neoplasms - secondary Uterus - blood supply Uterus - metabolism Uterus - pathology |
| title | Massive perivillous fibrin deposition in the placenta and uterine metastasis of gastric adenocarcinoma during pregnancy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T00%3A00%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Massive%20perivillous%20fibrin%20deposition%20in%20the%20placenta%20and%20uterine%20metastasis%20of%20gastric%20adenocarcinoma%20during%20pregnancy&rft.jtitle=The%20journal%20of%20obstetrics%20and%20gynaecology%20research&rft.au=Jeong,%20Bada&rft.date=2014-04&rft.volume=40&rft.issue=4&rft.spage=1150&rft.epage=1153&rft.pages=1150-1153&rft.issn=1341-8076&rft.eissn=1447-0756&rft_id=info:doi/10.1111/jog.12292&rft_dat=%3Cproquest_cross%3E1513051499%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1513051499&rft_id=info:pmid/24428779&rfr_iscdi=true |