A Patient with Diffuse Cutaneous Systemic Sclerosis Complicated by Antineutrophil-cytoplasmic Antibody-associated Vasculitis Exhibiting Honeycomb Lung without Volume Loss
We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung with...
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Veröffentlicht in: | Internal Medicine 2014, Vol.53(7), pp.801-804 |
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creator | Yamashita, Hiroyuki Takahashi, Yuko Kaneko, Hiroshi Kano, Toshikazu Mimori, Akio |
description | We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. It is necessary to recognise that vasculitis may develop in SSc patients who exhibit honeycomb lung without volume loss. |
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On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. 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Med.</addtitle><description>We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. It is necessary to recognise that vasculitis may develop in SSc patients who exhibit honeycomb lung without volume loss.</description><subject>Aged</subject><subject>Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - diagnosis</subject><subject>Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - etiology</subject><subject>Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology</subject><subject>Antibodies, Antineutrophil Cytoplasmic - immunology</subject><subject>antineutrophil cytoplasmic antibodies</subject><subject>Diagnosis, Differential</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Humans</subject><subject>interstitial lung disease</subject><subject>Lung Diseases - diagnosis</subject><subject>Lung Diseases - etiology</subject><subject>Peroxidase - immunology</subject><subject>Scleroderma, Diffuse - complications</subject><subject>Scleroderma, Diffuse - diagnosis</subject><subject>Scleroderma, Diffuse - immunology</subject><subject>sclerosis</subject><subject>Tomography, X-Ray Computed</subject><subject>vasculitis</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkc-O0zAQxi0EYsvCKyAfuaT4T5zEx6osLFIFSAt7tRxnsvXKiUNsC_JKPCUOLT0gLmOP5vfNjOZDCFOyZbSSb-0YYR61G6Czxo6wFXxLhZRP0IbyUhY14-Ip2hBJm4LlcIVehPBICG9qyZ6jK1ZWshSEbtCvHf6io4Ux4h82HvE72_cpAN6nqEfwKeC7JUQYrMF3xsHsgw1474fJWaMjdLhd8G6MeYcUZz8drSvMEv3kdFg1a6n13VLoELyxfxT3OpjkbMyNbn4ebZt_4wO-9SMsxg8tPqScrsv4FPG9d2kAfPAhvETPeu0CvDq_1-jb-5uv-9vi8PnDx_3uUBjBqliUnIEhvZCmN0RIbRoBTJOON6Ih0IuaGN21ouq7shQdbbu60Zo3Tcmhl5TV_Bq9OfWdZv89QYhqsMGAc6eDKCooJ2UlapHR5oSafJgwQ6-m2Q56XhQlanVK_euUElytTmXp6_OU1ObiRfjXmgx8OgGPIeoHuAB6jjY78d_O9RrOEy6gOepZwch_A8a5t4g</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Yamashita, Hiroyuki</creator><creator>Takahashi, Yuko</creator><creator>Kaneko, Hiroshi</creator><creator>Kano, Toshikazu</creator><creator>Mimori, Akio</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140101</creationdate><title>A Patient with Diffuse Cutaneous Systemic Sclerosis Complicated by Antineutrophil-cytoplasmic Antibody-associated Vasculitis Exhibiting Honeycomb Lung without Volume Loss</title><author>Yamashita, Hiroyuki ; Takahashi, Yuko ; Kaneko, Hiroshi ; Kano, Toshikazu ; Mimori, Akio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c526t-432ec0f59cfc059ac85e2a0d38580ef570cadb56fd445d1bd78aa38843ef91273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - diagnosis</topic><topic>Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - etiology</topic><topic>Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology</topic><topic>Antibodies, Antineutrophil Cytoplasmic - immunology</topic><topic>antineutrophil cytoplasmic antibodies</topic><topic>Diagnosis, Differential</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Humans</topic><topic>interstitial lung disease</topic><topic>Lung Diseases - diagnosis</topic><topic>Lung Diseases - etiology</topic><topic>Peroxidase - immunology</topic><topic>Scleroderma, Diffuse - complications</topic><topic>Scleroderma, Diffuse - diagnosis</topic><topic>Scleroderma, Diffuse - immunology</topic><topic>sclerosis</topic><topic>Tomography, X-Ray Computed</topic><topic>vasculitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yamashita, Hiroyuki</creatorcontrib><creatorcontrib>Takahashi, Yuko</creatorcontrib><creatorcontrib>Kaneko, Hiroshi</creatorcontrib><creatorcontrib>Kano, Toshikazu</creatorcontrib><creatorcontrib>Mimori, Akio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yamashita, Hiroyuki</au><au>Takahashi, Yuko</au><au>Kaneko, Hiroshi</au><au>Kano, Toshikazu</au><au>Mimori, Akio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Patient with Diffuse Cutaneous Systemic Sclerosis Complicated by Antineutrophil-cytoplasmic Antibody-associated Vasculitis Exhibiting Honeycomb Lung without Volume Loss</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>53</volume><issue>7</issue><spage>801</spage><epage>804</epage><pages>801-804</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. It is necessary to recognise that vasculitis may develop in SSc patients who exhibit honeycomb lung without volume loss.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>24694501</pmid><doi>10.2169/internalmedicine.53.1599</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - diagnosis Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - etiology Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology Antibodies, Antineutrophil Cytoplasmic - immunology antineutrophil cytoplasmic antibodies Diagnosis, Differential Fatal Outcome Female Humans interstitial lung disease Lung Diseases - diagnosis Lung Diseases - etiology Peroxidase - immunology Scleroderma, Diffuse - complications Scleroderma, Diffuse - diagnosis Scleroderma, Diffuse - immunology sclerosis Tomography, X-Ray Computed vasculitis |
title | A Patient with Diffuse Cutaneous Systemic Sclerosis Complicated by Antineutrophil-cytoplasmic Antibody-associated Vasculitis Exhibiting Honeycomb Lung without Volume Loss |
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