A Patient with Diffuse Cutaneous Systemic Sclerosis Complicated by Antineutrophil-cytoplasmic Antibody-associated Vasculitis Exhibiting Honeycomb Lung without Volume Loss

We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung with...

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Veröffentlicht in:Internal Medicine 2014, Vol.53(7), pp.801-804
Hauptverfasser: Yamashita, Hiroyuki, Takahashi, Yuko, Kaneko, Hiroshi, Kano, Toshikazu, Mimori, Akio
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container_issue 7
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container_title Internal Medicine
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creator Yamashita, Hiroyuki
Takahashi, Yuko
Kaneko, Hiroshi
Kano, Toshikazu
Mimori, Akio
description We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. It is necessary to recognise that vasculitis may develop in SSc patients who exhibit honeycomb lung without volume loss.
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Med.</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>53</volume><issue>7</issue><spage>801</spage><epage>804</epage><pages>801-804</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. 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subjects Aged
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - diagnosis
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - etiology
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology
Antibodies, Antineutrophil Cytoplasmic - immunology
antineutrophil cytoplasmic antibodies
Diagnosis, Differential
Fatal Outcome
Female
Humans
interstitial lung disease
Lung Diseases - diagnosis
Lung Diseases - etiology
Peroxidase - immunology
Scleroderma, Diffuse - complications
Scleroderma, Diffuse - diagnosis
Scleroderma, Diffuse - immunology
sclerosis
Tomography, X-Ray Computed
vasculitis
title A Patient with Diffuse Cutaneous Systemic Sclerosis Complicated by Antineutrophil-cytoplasmic Antibody-associated Vasculitis Exhibiting Honeycomb Lung without Volume Loss
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