Propensity Score Matching Analysis of Mechanical Versus Bioprosthetic Tricuspid Valve Replacements

Background Evidence for optimal prosthesis in the tricuspid position is lacking. We compared long-term results of tricuspid valve replacement (TVR) using mechanical and bioprosthetic valves. Methods From January 1994 to December 2012, 224 patients (male to female ratio = 55:169) underwent TVR. Mecha...

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Veröffentlicht in:The Annals of thoracic surgery 2014-04, Vol.97 (4), p.1294-1299
Hauptverfasser: Hwang, Ho Young, MD, PhD, Kim, Kyung-Hwan, MD, PhD, Kim, Ki-Bong, MD, PhD, Ahn, Hyuk, MD, PhD
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container_end_page 1299
container_issue 4
container_start_page 1294
container_title The Annals of thoracic surgery
container_volume 97
creator Hwang, Ho Young, MD, PhD
Kim, Kyung-Hwan, MD, PhD
Kim, Ki-Bong, MD, PhD
Ahn, Hyuk, MD, PhD
description Background Evidence for optimal prosthesis in the tricuspid position is lacking. We compared long-term results of tricuspid valve replacement (TVR) using mechanical and bioprosthetic valves. Methods From January 1994 to December 2012, 224 patients (male to female ratio = 55:169) underwent TVR. Mechanical TVR was performed in 121 patients (MTV group), and 103 patients underwent bioprosthetic TVR (BTV group). Patients in the BTV group were older and more frequently had hypertension than those in the MTV group. Propensity score matching was performed, and 66 patients were extracted from each group. Median follow-up duration was 73 (1 to 235) months. Operative results, long-term survival, and tricuspid valve-related events (TVRE) were compared. Results The ages of the propensity score-matched patients were 54.1 ± 8.7 and 55.3 ± 11.6 years in the MTV and BTV groups, respectively. Early mortality (n = 9, 6.8%) and postoperative complications were similar between the propensity score-matched groups. The 10-year overall survival and freedom from cardiac death rates were similar between the 2 matched groups ( p  = 0.897 and p  = 0.893, respectively). Freedom rates from a composite of thromboembolism and bleeding were lower in the MTV group than in the BTV group (83.6% and 77.4% vs 89.5% and 89.5% at 5 and 10 years, respectively), although it was not statistically significant. The TVRE-free rates at 10 years were 54.8% and 53.6% in the MTV and BTV groups, respectively. Conclusions Bioprosthetic valve replacement is a valid option for TVR in these relatively young patients because anticoagulation could be avoided without increasing the risks of long-term TVRE.
doi_str_mv 10.1016/j.athoracsur.2013.12.033
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We compared long-term results of tricuspid valve replacement (TVR) using mechanical and bioprosthetic valves. Methods From January 1994 to December 2012, 224 patients (male to female ratio = 55:169) underwent TVR. Mechanical TVR was performed in 121 patients (MTV group), and 103 patients underwent bioprosthetic TVR (BTV group). Patients in the BTV group were older and more frequently had hypertension than those in the MTV group. Propensity score matching was performed, and 66 patients were extracted from each group. Median follow-up duration was 73 (1 to 235) months. Operative results, long-term survival, and tricuspid valve-related events (TVRE) were compared. Results The ages of the propensity score-matched patients were 54.1 ± 8.7 and 55.3 ± 11.6 years in the MTV and BTV groups, respectively. Early mortality (n = 9, 6.8%) and postoperative complications were similar between the propensity score-matched groups. The 10-year overall survival and freedom from cardiac death rates were similar between the 2 matched groups ( p  = 0.897 and p  = 0.893, respectively). Freedom rates from a composite of thromboembolism and bleeding were lower in the MTV group than in the BTV group (83.6% and 77.4% vs 89.5% and 89.5% at 5 and 10 years, respectively), although it was not statistically significant. The TVRE-free rates at 10 years were 54.8% and 53.6% in the MTV and BTV groups, respectively. Conclusions Bioprosthetic valve replacement is a valid option for TVR in these relatively young patients because anticoagulation could be avoided without increasing the risks of long-term TVRE.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2013.12.033</identifier><identifier>PMID: 24565401</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Bioprosthesis ; Cardiothoracic Surgery ; Female ; Heart Valve Prosthesis ; Humans ; Male ; Middle Aged ; Propensity Score ; Prosthesis Design ; Retrospective Studies ; Surgery ; Time Factors ; Treatment Outcome ; Tricuspid Valve - surgery</subject><ispartof>The Annals of thoracic surgery, 2014-04, Vol.97 (4), p.1294-1299</ispartof><rights>The Society of Thoracic Surgeons</rights><rights>2014 The Society of Thoracic Surgeons</rights><rights>Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. 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We compared long-term results of tricuspid valve replacement (TVR) using mechanical and bioprosthetic valves. Methods From January 1994 to December 2012, 224 patients (male to female ratio = 55:169) underwent TVR. Mechanical TVR was performed in 121 patients (MTV group), and 103 patients underwent bioprosthetic TVR (BTV group). Patients in the BTV group were older and more frequently had hypertension than those in the MTV group. Propensity score matching was performed, and 66 patients were extracted from each group. Median follow-up duration was 73 (1 to 235) months. Operative results, long-term survival, and tricuspid valve-related events (TVRE) were compared. Results The ages of the propensity score-matched patients were 54.1 ± 8.7 and 55.3 ± 11.6 years in the MTV and BTV groups, respectively. Early mortality (n = 9, 6.8%) and postoperative complications were similar between the propensity score-matched groups. The 10-year overall survival and freedom from cardiac death rates were similar between the 2 matched groups ( p  = 0.897 and p  = 0.893, respectively). Freedom rates from a composite of thromboembolism and bleeding were lower in the MTV group than in the BTV group (83.6% and 77.4% vs 89.5% and 89.5% at 5 and 10 years, respectively), although it was not statistically significant. The TVRE-free rates at 10 years were 54.8% and 53.6% in the MTV and BTV groups, respectively. 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We compared long-term results of tricuspid valve replacement (TVR) using mechanical and bioprosthetic valves. Methods From January 1994 to December 2012, 224 patients (male to female ratio = 55:169) underwent TVR. Mechanical TVR was performed in 121 patients (MTV group), and 103 patients underwent bioprosthetic TVR (BTV group). Patients in the BTV group were older and more frequently had hypertension than those in the MTV group. Propensity score matching was performed, and 66 patients were extracted from each group. Median follow-up duration was 73 (1 to 235) months. Operative results, long-term survival, and tricuspid valve-related events (TVRE) were compared. Results The ages of the propensity score-matched patients were 54.1 ± 8.7 and 55.3 ± 11.6 years in the MTV and BTV groups, respectively. Early mortality (n = 9, 6.8%) and postoperative complications were similar between the propensity score-matched groups. The 10-year overall survival and freedom from cardiac death rates were similar between the 2 matched groups ( p  = 0.897 and p  = 0.893, respectively). Freedom rates from a composite of thromboembolism and bleeding were lower in the MTV group than in the BTV group (83.6% and 77.4% vs 89.5% and 89.5% at 5 and 10 years, respectively), although it was not statistically significant. The TVRE-free rates at 10 years were 54.8% and 53.6% in the MTV and BTV groups, respectively. Conclusions Bioprosthetic valve replacement is a valid option for TVR in these relatively young patients because anticoagulation could be avoided without increasing the risks of long-term TVRE.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>24565401</pmid><doi>10.1016/j.athoracsur.2013.12.033</doi><tpages>6</tpages></addata></record>
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Bioprosthesis
Cardiothoracic Surgery
Female
Heart Valve Prosthesis
Humans
Male
Middle Aged
Propensity Score
Prosthesis Design
Retrospective Studies
Surgery
Time Factors
Treatment Outcome
Tricuspid Valve - surgery
title Propensity Score Matching Analysis of Mechanical Versus Bioprosthetic Tricuspid Valve Replacements
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