Antimicrobial Activity of Endophytic Fungi Isolated from Swietenia macrophylla Leaves

The endophytic fungi isolated from leaves of Swietenia macrophylla of different ages were examined for antimicrobial activity. The agar plug diffusion assay was used for primary screening, followed by the disc diffusion method. A total of 461 filamentous endophytic fungi were isolated and cultured t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Natural product communications 2014-02, Vol.9 (2), p.247-250
Hauptverfasser: Ibrahim, Darah, Lee, Chong Chai, Sheh-Hong, Lim
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 250
container_issue 2
container_start_page 247
container_title Natural product communications
container_volume 9
creator Ibrahim, Darah
Lee, Chong Chai
Sheh-Hong, Lim
description The endophytic fungi isolated from leaves of Swietenia macrophylla of different ages were examined for antimicrobial activity. The agar plug diffusion assay was used for primary screening, followed by the disc diffusion method. A total of 461 filamentous endophytic fungi were isolated and cultured to examine their antimicrobial properties. In the primary screen, 315 isolates (68.3%) exhibited activity against at least one of the test pathogenic microorganisms. The percentage of isolates exhibiting antimicrobial activity increased with leaf age. Endophytic fungal assemblages, as well as those isolates exhibiting antimicrobial properties appeared to increase with leaf age. The main antimicrobial compounds were produced extracellularly by the endophytic fungi. The results suggest that healthy leaves at older stages of growth can be a potential source for the isolation of endophytic fungi with antimicrobial properties.
doi_str_mv 10.1177/1934578X1400900229
format Article
fullrecord <record><control><sourceid>proquest_AFRWT</sourceid><recordid>TN_cdi_proquest_miscellaneous_1512558009</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1934578X1400900229</sage_id><sourcerecordid>1512558009</sourcerecordid><originalsourceid>FETCH-LOGICAL-c387t-b02f2569412451d8af5098bf62abf0235348e105239aa6c1caa58ad0fa10e4883</originalsourceid><addsrcrecordid>eNp9kDFPwzAQhS0EolXpH2BAHlkCtmM39lhVLVSqxACV2KJLYhdXSVxip6j_HlctLEjccjd87-ndQ-iWkgdKs-yRqpSLTL5TTogihDF1gYZUCJEononLeEcgORIDNPZ-S-JIyQlX12jA-ESqlLAhWk_bYBtbdq6wUONpGezehgN2Bs_byu0-DsGWeNG3G4uX3tUQdIVN5xr8-mV10K0F3ECUR7KuAa807LW_QVcGaq_H5z1C68X8bfacrF6elrPpKilTmYWkIMwwMVGcMi5oJcEIomRhJgwKQ1gqUi41JYKlCmBS0hJASKiIAUo0lzIdofuT765zn732IW-sL3UM0mrX-5wKyoSQsaGIshMas3rfaZPvOttAd8gpyY-N5n8bjaK7s39fNLr6lfz0F4HHE-Bho_Ot67s2_vuf5TcXwn4e</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1512558009</pqid></control><display><type>article</type><title>Antimicrobial Activity of Endophytic Fungi Isolated from Swietenia macrophylla Leaves</title><source>Sage Journals GOLD Open Access 2024</source><creator>Ibrahim, Darah ; Lee, Chong Chai ; Sheh-Hong, Lim</creator><creatorcontrib>Ibrahim, Darah ; Lee, Chong Chai ; Sheh-Hong, Lim</creatorcontrib><description>The endophytic fungi isolated from leaves of Swietenia macrophylla of different ages were examined for antimicrobial activity. The agar plug diffusion assay was used for primary screening, followed by the disc diffusion method. A total of 461 filamentous endophytic fungi were isolated and cultured to examine their antimicrobial properties. In the primary screen, 315 isolates (68.3%) exhibited activity against at least one of the test pathogenic microorganisms. The percentage of isolates exhibiting antimicrobial activity increased with leaf age. Endophytic fungal assemblages, as well as those isolates exhibiting antimicrobial properties appeared to increase with leaf age. The main antimicrobial compounds were produced extracellularly by the endophytic fungi. The results suggest that healthy leaves at older stages of growth can be a potential source for the isolation of endophytic fungi with antimicrobial properties.</description><identifier>ISSN: 1934-578X</identifier><identifier>EISSN: 1555-9475</identifier><identifier>DOI: 10.1177/1934578X1400900229</identifier><identifier>PMID: 24689302</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Anti-Infective Agents - isolation &amp; purification ; Endophytes - isolation &amp; purification ; Fungi - isolation &amp; purification ; Meliaceae - microbiology ; Microbial Sensitivity Tests ; Plant Leaves - microbiology</subject><ispartof>Natural product communications, 2014-02, Vol.9 (2), p.247-250</ispartof><rights>2014 SAGE Publications Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-b02f2569412451d8af5098bf62abf0235348e105239aa6c1caa58ad0fa10e4883</citedby><cites>FETCH-LOGICAL-c387t-b02f2569412451d8af5098bf62abf0235348e105239aa6c1caa58ad0fa10e4883</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1934578X1400900229$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1934578X1400900229$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21946,27832,27903,27904,44924,45312</link.rule.ids><linktorsrc>$$Uhttps://journals.sagepub.com/doi/full/10.1177/1934578X1400900229?utm_source=summon&amp;utm_medium=discovery-provider$$EView_record_in_SAGE_Publications$$FView_record_in_$$GSAGE_Publications</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24689302$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ibrahim, Darah</creatorcontrib><creatorcontrib>Lee, Chong Chai</creatorcontrib><creatorcontrib>Sheh-Hong, Lim</creatorcontrib><title>Antimicrobial Activity of Endophytic Fungi Isolated from Swietenia macrophylla Leaves</title><title>Natural product communications</title><addtitle>Nat Prod Commun</addtitle><description>The endophytic fungi isolated from leaves of Swietenia macrophylla of different ages were examined for antimicrobial activity. The agar plug diffusion assay was used for primary screening, followed by the disc diffusion method. A total of 461 filamentous endophytic fungi were isolated and cultured to examine their antimicrobial properties. In the primary screen, 315 isolates (68.3%) exhibited activity against at least one of the test pathogenic microorganisms. The percentage of isolates exhibiting antimicrobial activity increased with leaf age. Endophytic fungal assemblages, as well as those isolates exhibiting antimicrobial properties appeared to increase with leaf age. The main antimicrobial compounds were produced extracellularly by the endophytic fungi. The results suggest that healthy leaves at older stages of growth can be a potential source for the isolation of endophytic fungi with antimicrobial properties.</description><subject>Anti-Infective Agents - isolation &amp; purification</subject><subject>Endophytes - isolation &amp; purification</subject><subject>Fungi - isolation &amp; purification</subject><subject>Meliaceae - microbiology</subject><subject>Microbial Sensitivity Tests</subject><subject>Plant Leaves - microbiology</subject><issn>1934-578X</issn><issn>1555-9475</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDFPwzAQhS0EolXpH2BAHlkCtmM39lhVLVSqxACV2KJLYhdXSVxip6j_HlctLEjccjd87-ndQ-iWkgdKs-yRqpSLTL5TTogihDF1gYZUCJEononLeEcgORIDNPZ-S-JIyQlX12jA-ESqlLAhWk_bYBtbdq6wUONpGezehgN2Bs_byu0-DsGWeNG3G4uX3tUQdIVN5xr8-mV10K0F3ECUR7KuAa807LW_QVcGaq_H5z1C68X8bfacrF6elrPpKilTmYWkIMwwMVGcMi5oJcEIomRhJgwKQ1gqUi41JYKlCmBS0hJASKiIAUo0lzIdofuT765zn732IW-sL3UM0mrX-5wKyoSQsaGIshMas3rfaZPvOttAd8gpyY-N5n8bjaK7s39fNLr6lfz0F4HHE-Bho_Ot67s2_vuf5TcXwn4e</recordid><startdate>201402</startdate><enddate>201402</enddate><creator>Ibrahim, Darah</creator><creator>Lee, Chong Chai</creator><creator>Sheh-Hong, Lim</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201402</creationdate><title>Antimicrobial Activity of Endophytic Fungi Isolated from Swietenia macrophylla Leaves</title><author>Ibrahim, Darah ; Lee, Chong Chai ; Sheh-Hong, Lim</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-b02f2569412451d8af5098bf62abf0235348e105239aa6c1caa58ad0fa10e4883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Anti-Infective Agents - isolation &amp; purification</topic><topic>Endophytes - isolation &amp; purification</topic><topic>Fungi - isolation &amp; purification</topic><topic>Meliaceae - microbiology</topic><topic>Microbial Sensitivity Tests</topic><topic>Plant Leaves - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ibrahim, Darah</creatorcontrib><creatorcontrib>Lee, Chong Chai</creatorcontrib><creatorcontrib>Sheh-Hong, Lim</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Natural product communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ibrahim, Darah</au><au>Lee, Chong Chai</au><au>Sheh-Hong, Lim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antimicrobial Activity of Endophytic Fungi Isolated from Swietenia macrophylla Leaves</atitle><jtitle>Natural product communications</jtitle><addtitle>Nat Prod Commun</addtitle><date>2014-02</date><risdate>2014</risdate><volume>9</volume><issue>2</issue><spage>247</spage><epage>250</epage><pages>247-250</pages><issn>1934-578X</issn><eissn>1555-9475</eissn><abstract>The endophytic fungi isolated from leaves of Swietenia macrophylla of different ages were examined for antimicrobial activity. The agar plug diffusion assay was used for primary screening, followed by the disc diffusion method. A total of 461 filamentous endophytic fungi were isolated and cultured to examine their antimicrobial properties. In the primary screen, 315 isolates (68.3%) exhibited activity against at least one of the test pathogenic microorganisms. The percentage of isolates exhibiting antimicrobial activity increased with leaf age. Endophytic fungal assemblages, as well as those isolates exhibiting antimicrobial properties appeared to increase with leaf age. The main antimicrobial compounds were produced extracellularly by the endophytic fungi. The results suggest that healthy leaves at older stages of growth can be a potential source for the isolation of endophytic fungi with antimicrobial properties.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>24689302</pmid><doi>10.1177/1934578X1400900229</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier ISSN: 1934-578X
ispartof Natural product communications, 2014-02, Vol.9 (2), p.247-250
issn 1934-578X
1555-9475
language eng
recordid cdi_proquest_miscellaneous_1512558009
source Sage Journals GOLD Open Access 2024
subjects Anti-Infective Agents - isolation & purification
Endophytes - isolation & purification
Fungi - isolation & purification
Meliaceae - microbiology
Microbial Sensitivity Tests
Plant Leaves - microbiology
title Antimicrobial Activity of Endophytic Fungi Isolated from Swietenia macrophylla Leaves
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T11%3A28%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_AFRWT&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Antimicrobial%20Activity%20of%20Endophytic%20Fungi%20Isolated%20from%20Swietenia%20macrophylla%20Leaves&rft.jtitle=Natural%20product%20communications&rft.au=Ibrahim,%20Darah&rft.date=2014-02&rft.volume=9&rft.issue=2&rft.spage=247&rft.epage=250&rft.pages=247-250&rft.issn=1934-578X&rft.eissn=1555-9475&rft_id=info:doi/10.1177/1934578X1400900229&rft_dat=%3Cproquest_AFRWT%3E1512558009%3C/proquest_AFRWT%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1512558009&rft_id=info:pmid/24689302&rft_sage_id=10.1177_1934578X1400900229&rfr_iscdi=true