Dosimetric Feasibility and Acute Toxicity in a Prospective Trial of Ultrashort-Course Accelerated Partial Breast Irradiation (APBI) Using a Multi-Lumen Balloon Brachytherapy Device

Background Shorter courses of APBI, including single-fraction intraoperative therapy, are under active investigation. We designed a prospective trial to identify and address the potential radiobiological and logistical shortcomings of single-fraction APBI. Methods We designed a single-arm, multi-ins...

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Veröffentlicht in:	Annals of surgical oncology 2013-04, Vol.20 (4), p.1295-1301
Hauptverfasser:	Khan, A. J., Vicini, F. A., Brown, S., Haffty, B. G., Kearney, Thomas, Dale, R., Lyden, M., Arthur, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Brachytherapy - adverse effects Brachytherapy - instrumentation Breast Neoplasms - pathology Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Breast Oncology Carcinoma, Ductal - pathology Carcinoma, Ductal - radiotherapy Carcinoma, Ductal - surgery Carcinoma, Lobular - pathology Carcinoma, Lobular - radiotherapy Carcinoma, Lobular - surgery Catheterization Feasibility Studies Female Follow-Up Studies Humans Mastectomy Medicine Medicine & Public Health Middle Aged Neoplasm Grading Neoplasm Invasiveness Neoplasm Staging Oncology Prognosis Prospective Studies Radiation Injuries - etiology Radiation Injuries - prevention & control Radiometry Surgery Surgical Oncology Survival Rate
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