Comparative Genomic and Proteomic Anatomy of Mycobacterium Ubiquitous Esx Family Proteins: Implications in Pathogenicity and Virulence

Secreted proteins are among the most important molecules involved in host—pathogen interaction of Mycobacterium tuberculosis, the etiological agent of human tuberculosis (TB). M. tuberculosis encodes five types of VII secretion systems (ESX-1 to ESX-5) responsible for the exportation of many protein...

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Veröffentlicht in:	Current microbiology 2014-04, Vol.68 (4), p.558-567
Hauptverfasser:	Deng, Wanyan, Xiang, Xiaohong, Xie, Jianping
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - chemistry Bacterial Proteins - genetics Biomedical and Life Sciences Biotechnology Comparative studies drugs evolution Genes, Bacterial - genetics genome Genomics Genomics - methods Life Sciences Microbiology Molecular Sequence Data Multigene Family mutation Mycobacterium - genetics Mycobacterium - pathogenicity Mycobacterium tuberculosis Pathogenesis Pathogens phosphorylation Proteins Proteomics Proteomics - methods secretion Sequence Alignment serine threonine Tuberculosis virulence Virulence - genetics
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