Pyrene-labeled pyrrolidinyl peptide nucleic acid as a hybridization-responsive DNA probe: comparison between internal and terminal labeling

Nucleic acids or nucleic acid analogues carrying an environment sensitive fluorophore that can change optical properties in response to hybridization with complementary DNA or RNA targets are potentially useful as self-reporting hybridization probes that do not require a quencher. In this study, pyr...

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Veröffentlicht in:RSC advances 2014, Vol.4 (17), p.8817-8827
Hauptverfasser: Boonlua, Chalothorn, Ditmangklo, Boonsong, Reenabthue, Nisanath, Suparpprom, Chaturong, Poomsuk, Nattawee, Siriwong, Khatcharin, Vilaivan, Tirayut
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Sprache:eng
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