MMPs in the neuroretina and optic nerve: modulators of glaucoma pathogenesis and repair?

Multiple studies in glaucoma patients and in animal models of spontaneous and experimentally-induced glaucoma, reported changes in the expression and activity of several matrix metalloproteinases (MMPs) in the retina, optic nerve, aqueous humor, and trabecular meshwork. These data have led to the hy...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2014-03, Vol.55 (3), p.1953-1964
Hauptverfasser:	De Groef, Lies, Van Hove, Inge, Dekeyster, Eline, Stalmans, Ingeborg, Moons, Lieve
Format:	Artikel
Sprache:	eng
Schlagworte:	Glaucoma - enzymology Glaucoma - pathology Glaucoma - physiopathology Humans Intraocular Pressure Matrix Metalloproteinases - biosynthesis Optic Nerve - enzymology Optic Nerve - pathology Retinal Ganglion Cells - enzymology Retinal Ganglion Cells - pathology
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