Effect of Antispastic Drugs on Motor Reflexes and Voluntary Muscle Contraction in Incomplete Spinal Cord Injury

Abstract Objective To investigate the effects of antispastic drugs baclofen and tizanidine on reflexes and volitional tasks. Design Double-blind, placebo-controlled, crossover, before-after trial, pilot study. Setting Research laboratory in a rehabilitation hospital. Participants Men with chronic (&...

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Veröffentlicht in:	Archives of physical medicine and rehabilitation 2014-04, Vol.95 (4), p.622-632
Hauptverfasser:	Chu, Virginia Way Tong, PhD, Hornby, Thomas George, PhD, PT, Schmit, Brian David, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Baclofen - pharmacology Clonidine - analogs & derivatives Clonidine - pharmacology Cross-Over Studies Double-Blind Method Electromyography Humans Isometric Contraction - drug effects Isometric Contraction - physiology Lower Extremity - physiopathology Male Middle Aged Muscle Relaxants, Central - pharmacology Muscle spasticity Muscle strength Muscle Strength - drug effects Muscle Strength - physiology Physical Medicine and Rehabilitation Pilot Projects Reflex, stretch Reflex, Stretch - drug effects Reflex, Stretch - physiology Rehabilitation Spinal cord injuries Spinal Cord Injuries - physiopathology Torque
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