Autoantibodies to RuvBL1 and RuvBL2: A Novel Systemic Sclerosis–Related Antibody Associated With Diffuse Cutaneous and Skeletal Muscle Involvement

Objective To identify and characterize a novel systemic sclerosis (SSc)–related autoantibody directed against a complex consisting of RuvBL1 and RuvBL2 (RuvBL1/2) and to assess its clinical correlations. Methods We first analyzed 316 consecutive patients with SSc who were evaluated at Kanazawa Unive...

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Veröffentlicht in:	Arthritis care & research (2010) 2014-04, Vol.66 (4), p.575-584
Hauptverfasser:	Kaji, Kenzou, Fertig, Noreen, Medsger, Thomas A., Satoh, Takashi, Hoshino, Kana, Hamaguchi, Yasuhito, Hasegawa, Minoru, Lucas, Mary, Schnure, Andrew, Ogawa, Fumihide, Sato, Shinichi, Takehara, Kazuhiko, Fujimoto, Manabu, Kuwana, Masataka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibodies, Antinuclear - blood ATPases Associated with Diverse Cellular Activities Biomarkers - blood Carrier Proteins - immunology Case-Control Studies Cohort Studies DNA Helicases - immunology Female Humans Male Middle Aged Myositis - complications Myositis - immunology Scleroderma, Diffuse - blood Scleroderma, Diffuse - complications Scleroderma, Diffuse - immunology Young Adult
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