Mangromicins A and B: structure and antitrypanosomal activity of two new cyclopentadecane compounds from Lechevalieria aerocolonigenes K10-0216

Two new cyclopentadecane antibiotics, named mangromicins A and B, were separated out from the culture broth of Lechevalieria aerocolonigenes K10-0216 by Diaion HP-20, silica gel and ODS column chromatography, and were finally purified by HPLC. The chemical structures of the two novel compounds were...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 2014-03, Vol.67 (3), p.253-260
Hauptverfasser:	Nakashima, Takuji, Iwatsuki, Masato, Ochiai, Junya, Kamiya, Yoshiyuki, Nagai, Kenichiro, Matsumoto, Atsuko, Ishiyama, Aki, Otoguro, Kazuhiko, Shiomi, Kazuro, Takahashi, Yōko, Ōmura, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647/2258 631/326/252/22/1290 Actinomycetales - chemistry Antibiotics Bacteriology Biomedical and Life Sciences Bioorganic Chemistry Chromatography Chromatography, High Pressure Liquid Crystallography Crystallography, X-Ray Cytotoxicity Fibroblasts - drug effects Fibroblasts - metabolism Humans Inhibitory Concentration 50 Life Sciences Liquid chromatography Lung - cytology Lung - drug effects Lung - metabolism Macrolides - chemistry Macrolides - isolation & purification Macrolides - pharmacology Magnetic Resonance Spectroscopy Mass Spectrometry Medicinal Chemistry Microbiology Organic Chemistry original-article Silica Silica Gel Toxicity Tests Trypanocidal Agents - chemistry Trypanocidal Agents - isolation & purification Trypanocidal Agents - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!