Microfluidic bead-based sensing platform for monitoring kinase activity

Protein kinases control cellular functions by regulating protein phosphorylation. Monitoring protein kinase activity is essential for medical diagnosis and drug screening. Here, we present a novel microfluidic device for performing simple and versatile protein kinase assays, which utilizes a microbe...

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Veröffentlicht in:	Biosensors & bioelectronics 2014-07, Vol.57, p.1-9
Hauptverfasser:	Lee, Seung Hwan, Rhee, Hyun-Woo, van Noort, Danny, Lee, Hong Jai, Park, Hee Ho, Shin, Ik-Soo, Hong, Jong-In, Park, Tai Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biosensing Techniques - instrumentation Biotechnology Chemosensor Enzyme Assays - instrumentation Equipment Design Fundamental and applied biological sciences. Psychology HeLa Cells Humans Kinase assay Microfluidic Analytical Techniques - instrumentation Microfluidic device Peptides - metabolism Phosphorylation Protein kinase activity Protein Kinases - metabolism
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