Sulfur rich 2-mercaptobenzothiazole and 1,2,3-triazole conjugates as novel antitubercular agents

A series of benzfused heterocyclic derivatives such as amide conjugates of 2-(benzo[d]thiazol-2-ylthio)acetic acid with aromatic/aliphatic/cyclic secondary amines (5a–5o & 8a–8m); 1,2,3-triazole conjugates of 2-mercaptobenzothiazoles and amide conjugates of indole-3-glyoxalic acid with cyclic se...

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Veröffentlicht in:	European journal of medicinal chemistry 2014-04, Vol.76, p.274-283
Hauptverfasser:	Mir, Fauzia, Shafi, Syed, Zaman, M.S., Kalia, Nitin Pal, Rajput, Vikrant S., Mulakayala, Chaitanya, Mulakayala, Naveen, Khan, Inshad A., Alam, M.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2,3-Triazole Antitubercular activity Antitubercular Agents - pharmacology Bactericidal Benzothiazole Benzothiazoles - chemistry Benzothiazoles - pharmacology H37Rv Indole-3-glyoxalic acid Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Molecular Docking Simulation Mycobacterium tuberculosis - drug effects Spectrometry, Mass, Electrospray Ionization Sulfur - analysis
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