S‑Aroylthiooximes: A Facile Route to Hydrogen Sulfide Releasing Compounds with Structure-Dependent Release Kinetics

We report the facile preparation of a family of S-aroylthiooxime (SATO) H2S donors, which are synthesized via a click reaction analogous to oxime formation between S-aroylthio­hydroxyl­amines (SATHAs) and aldehydes or ketones. Analysis of cysteine-triggered H2S release revealed structure-dependent r...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic letters 2014-03, Vol.16 (6), p.1558-1561
Hauptverfasser:	Foster, Jeffrey C, Powell, Chadwick R, Radzinski, Scott C, Matson, John B
Format:	Artikel
Sprache:	eng
Schlagworte:	Cysteine - chemistry Half-Life Hydrogen Sulfide - chemistry Kinetics Molecular Structure Oximes - chemistry Sulfur Compounds - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!