Cinanthrenol A, an Estrogenic Steroid Containing Phenanthrene Nucleus, from a Marine Sponge Cinachyrella sp

Cinanthrenol A (1), a new steroid composed of a phenanthrene and a spiro[2,4]heptane system, was isolated from the marine sponge Cinachyrella sp. It is the first phenathrene-containing steroid with estrogen activity.

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Veröffentlicht in:Organic letters 2014-03, Vol.16 (6), p.1539-1541
Hauptverfasser: Machida, Koshi, Abe, Takahiro, Arai, Daisuke, Okamoto, Mayumi, Shimizu, Isao, de Voogd, Nicole J, Fusetani, Nobuhiro, Nakao, Yoichi
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container_end_page 1541
container_issue 6
container_start_page 1539
container_title Organic letters
container_volume 16
creator Machida, Koshi
Abe, Takahiro
Arai, Daisuke
Okamoto, Mayumi
Shimizu, Isao
de Voogd, Nicole J
Fusetani, Nobuhiro
Nakao, Yoichi
description Cinanthrenol A (1), a new steroid composed of a phenanthrene and a spiro[2,4]heptane system, was isolated from the marine sponge Cinachyrella sp. It is the first phenathrene-containing steroid with estrogen activity.
doi_str_mv 10.1021/ol5000023
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ispartof Organic letters, 2014-03, Vol.16 (6), p.1539-1541
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source ACS Publications; MEDLINE
subjects Animals
Estrogens - chemistry
Estrogens - isolation & purification
Estrogens - pharmacology
Humans
Marine Biology
Molecular Structure
Phenanthrenes - chemistry
Porifera - chemistry
Steroids - chemistry
Steroids - isolation & purification
Steroids - pharmacology
title Cinanthrenol A, an Estrogenic Steroid Containing Phenanthrene Nucleus, from a Marine Sponge Cinachyrella sp
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