Regulation of murine MHC class II molecule expression. Identification of A sub(beta) residues responsible for allele-specific cell surface expression

A panel of mutant class II genes have been constructed using site-directed mutagenesis and DNA-mediated gene transfer. Using this technique, A super(k) beta polypeptides have been altered by substituting one or more A super(d) beta-specific residues at polymorphic positions in the beta sub(1) domain...

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Veröffentlicht in:The Journal of experimental medicine 1988-01, Vol.168 (3), p.823-837
Hauptverfasser: Buerstedde, J-M, Pease, L R, Nilson, A E, Bell, M P, Chase, G, Buerstedde, G, McKean, D J
Format: Artikel
Sprache:eng
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