The repeated dose toxicity of a zinc oxide/hexachloroethane smoke

Mice, rats and guinea pigs were exposed to the smoke produced by ignition of a zinc oxide/hexachloroethane pyrotechnic composition, 1 h/day, 5 days/week, at three different dose levels, together with controls. The animals received 100 exposures except for the high dose guinea pigs, which underwent 1...

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Veröffentlicht in:	Archives of toxicology 1988, Vol.62 (2-3), p.123-132
Hauptverfasser:	Marrs, T C, Colgrave, H F, Edginton, J A, Brown, R F, Cross, N L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dose-Response Relationship, Drug Ethane - analogs & derivatives Female Guinea Pigs Hydrocarbons, Chlorinated - toxicity Lung - pathology Lung Neoplasms - etiology Mice Organ Size - drug effects Smoke - adverse effects Smoke - analysis Zinc - toxicity Zinc Oxide - toxicity
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