Urokinase plasminogen activator gene deficiency inhibits fracture cartilage remodeling

Urokinase plasminogen activator (uPA) regulates a proteolytic cascade of extracellular matrix degradation that functions in tissue development and tissue repair. The development and remodeling of the skeletal extracellular matrix during wound healing suggests that uPA might regulate bone development...

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Veröffentlicht in:	Journal of bone and mineral metabolism 2014-03, Vol.32 (2), p.124-135
Hauptverfasser:	Popa, Nicoleta L., Wergedal, Jon E., Lau, K.-H. William, Mohan, Subburaman, Rundle, Charles H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cartilage - metabolism Cartilage - pathology Fracture Healing - genetics Gene Expression Regulation Medicine Medicine & Public Health Metabolic Diseases Mice Mice, Knockout Original Article Orthopedics Polymerase Chain Reaction Urokinase-Type Plasminogen Activator - genetics
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