SGLT2 selective inhibitor ipragliflozin reduces body fat mass by increasing fatty acid oxidation in high-fat diet-induced obese rats

Ipragliflozin is a novel and selective sodium–glucose cotransporter 2 (SGLT2) inhibitor that induces sustained increases in urinary glucose excretion by inhibiting renal glucose reabsorption and thereby exerting a subsequent antihyperglycemic effect. Here, we examined the effect of ipragliflozin on...

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Veröffentlicht in:European journal of pharmacology 2014-03, Vol.727, p.66-74
Hauptverfasser: Yokono, Masanori, Takasu, Toshiyuki, Hayashizaki, Yuka, Mitsuoka, Keisuke, Kihara, Rumi, Muramatsu, Yuko, Miyoshi, Sousuke, Tahara, Atsuo, Kurosaki, Eiji, Li, Qun, Tomiyama, Hiroshi, Sasamata, Masao, Shibasaki, Masayuki, Uchiyama, Yasuo
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Sprache:eng ; jpn
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